MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner
about
Inhibition of Tat activity by the HEXIM1 proteinCompensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcriptionHEXIM2, a HEXIM1-related protein, regulates positive transcription elongation factor b through association with 7SKIdentification of HEXIM1 as a positive regulator of p53HEXIM1 forms a transcriptionally abortive complex with glucocorticoid receptor without involving 7SK RNA and positive transcription elongation factor bAcetylation of conserved lysines in the catalytic core of cyclin-dependent kinase 9 inhibits kinase activity and regulates transcriptionSystematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzymeThe structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylationA human immunodeficiency virus type 1 Tat-like arginine-rich RNA-binding domain is essential for HEXIM1 to inhibit RNA polymerase II transcription through 7SK snRNA-mediated inactivation of P-TEFbBinding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitorCrystal structure of HIV-1 Tat complexed with human P-TEFbLARP7 is a stable component of the 7SK snRNP while P-TEFb, HEXIM1 and hnRNP A1 are reversibly associatedRegulation of P-TEFb elongation complex activity by CDK9 acetylationA new paradigm in eukaryotic biology: HIV Tat and the control of transcriptional elongationOligomerization of HEXIM1 via 7SK snRNA and coiled-coil region directs the inhibition of P-TEFbRoles of microRNAs and long-noncoding RNAs in human immunodeficiency virus replicationCyclin Box Structure of the P-TEFb Subunit Cyclin T1 Derived from a Fusion Complex with EIAV TatStructure of the Cyclin T binding domain of Hexim1 and molecular basis for its recognition of P-TEFbStructural insights into the cyclin T1-Tat-TAR RNA transcription activation complex from EIAVThe structure of CDK4/cyclin D3 has implications for models of CDK activationIdentification of a cyclin T-binding domain in Hexim1 and biochemical analysis of its binding competition with HIV-1 TatThe breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186Transcription-dependent association of multiple positive transcription elongation factor units to a HEXIM multimerCracking the control of RNA polymerase II elongation by 7SK snRNP and P-TEFbSmall molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytesHEXIM1 induces differentiation of human pluripotent stem cells9-Aminoacridine inhibition of HIV-1 Tat dependent transcription.A real-time view of the TAR:Tat:P-TEFb complex at HIV-1 transcription sitesHMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription.Cellular mRNA activates transcription elongation by displacing 7SK RNA.Cell-type-specific proteome and interactome: using HIV-1 Tat as a test case.Cyclin T1-dependent genes in activated CD4 T and macrophage cell lines appear enriched in HIV-1 co-factors.Phosphatase PPM1A regulates phosphorylation of Thr-186 in the Cdk9 T-loop.The crystal structure of the 5΄ functional domain of the transcription riboregulator 7SK.A capping-independent function of MePCE in stabilizing 7SK snRNA and facilitating the assembly of 7SK snRNP.Controlling cellular P-TEFb activity by the HIV-1 transcriptional transactivator TatMechanism and factors that control HIV-1 transcription and latency activationProtein phosphatase-1 activates CDK9 by dephosphorylating Ser175.
P2860
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P2860
MAQ1 and 7SK RNA interact with CDK9/cyclin T complexes in a transcription-dependent manner
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@ast
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@en
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@nl
type
label
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@ast
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@en
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@nl
prefLabel
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@ast
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@en
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@nl
P2093
P2860
P921
P3181
P1476
MAQ1 and 7SK RNA interact with ...... transcription-dependent manner
@en
P2093
Alessandro Fraldi
François Bonnet
Luigi Lania
Mia Edwards
Olivier Bensaude
Valérie Labas
Van Trung Nguyen
P2860
P304
P3181
P356
10.1128/MCB.23.14.4859-4869.2003
P407
P577
2003-07-01T00:00:00Z