Identification of direct protein targets of small molecules - Test2 - elhamkhani - TriplyDB

Identification of direct protein targets of small molecules

Identification of direct protein targets of small molecules

http://www.wikidata.org/entity/Q21558640

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Plant chemical biology: are we meeting the promise?Small-molecule based musculoskeletal regenerative engineering Flow-Based Single Cell Deposition for High-Throughput Screening of Protein Libraries N (6)-substituted AMPs inhibit mammalian deoxynucleotide N-hydrolase DNPH1 Target identification by image analysis Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells Approaches to Validate and Manipulate RNA Targets with Small Molecules in Cells Systems pharmacology uncovers Janus functions of botanical drugs: activation of host defense system and inhibition of influenza virus replication.Examination of the mode of action of the almiramide family of natural products against the kinetoplastid parasite Trypanosoma brucei.Considerations for designing chemical screening strategies in plant biology.Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.Marine natural products: a new wave of drugs?Kinetic capillary electrophoresis with mass-spectrometry detection (KCE-MS) facilitates label-free solution-based kinetic analysis of protein-small molecule binding.The impact of plant-pathogen studies on medicinal drug discovery.Synthesis and evaluation of indole-based chalcones as inducers of methuosis, a novel type of nonapoptotic cell death.Active/inactive dual-probe system for selective photoaffinity labeling of small molecule-binding proteins.Substrate-baited nanoparticles: a catch and release strategy for enzyme recognition and harvesting.The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR.Identification of small molecule inhibitors of cytokinesis and single cell wound repair.Target identification of small molecules based on chemical biology approaches.Target identification for small bioactive molecules: finding the needle in the haystack.Target identification and mechanism of action in chemical biology and drug discovery.Targeting poly (ADP-ribose) polymerase partially contributes to bufalin-induced cell death in multiple myeloma cells.Mass spectrometry imaging for drugs and metabolites.Cell-based protein stabilization assays for the detection of interactions between small-molecule inhibitors and BRD4.Drug affinity responsive target stability (DARTS) for small-molecule target identification.Photoaffinity labeling in target- and binding-site identification Target identification using drug affinity responsive target stability (DARTS).Utilizing Yeast Surface Human Proteome Display Libraries to Identify Small Molecule-Protein Interactions.Identification of H7 as a novel peroxiredoxin I inhibitor to induce differentiation of leukemia cells.Proteome-wide Identification of Novel Ceramide-binding Proteins by Yeast Surface cDNA Display and Deep Sequencing Target identification for biologically active small molecules using chemical biology approaches.Identification of protein binding partners of small molecules using label-free methods.Investigating metabolite-protein interactions: an overview of available techniques.MOST: most-similar ligand based approach to target prediction.The Chemistry and Biology of Nakiterpiosin - C-nor-D-Homosteroids.The antimalarial natural product symplostatin 4 is a nanomolar inhibitor of the food vacuole falcipains.Systems Pharmacology Uncovers the Multiple Mechanisms of Xijiao Dihuang Decoction for the Treatment of Viral Hemorrhagic Fever

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P2860

Identification of direct protein targets of small molecules

http://www.wikidata.org/entity/Q21558640

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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2011年论文

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name

Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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Identification of direct protein targets of small molecules

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ACS Chemical Biology

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Identification of direct protein targets of small molecules

@en

P2093

Brett Lomenick

http://www.w3.org/2001/XMLSchema#string

Jing Huang

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Richard W Olsen

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P2860

Pulse proteolysis: A simple method for quantitative determination of protein stability and ligand binding

A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolyl isomerase

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.

High resolution two-dimensional electrophoresis of proteins

Discovery of a proneurogenic, neuroprotective chemical

Selective enzyme purification by affinity chromatography

Isolation of the lac repressor

Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

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34-46

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scholarly article

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2034274

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10.1021/CB100294V

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1

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6

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2011-01-21T00:00:00Z

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47793058

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21077692

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biomedical investigative technique

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3031183

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