Discovery of a proneurogenic, neuroprotective chemical - Test2 - elhamkhani - TriplyDB

Discovery of a proneurogenic, neuroprotective chemical

Discovery of a proneurogenic, neuroprotective chemical

http://www.wikidata.org/entity/Q24620801

about

Identification of direct protein targets of small molecules Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)Alzheimer's Disease and Hippocampal Adult Neurogenesis; Exploring Shared Mechanisms Insights into the Biology and Therapeutic Applications of Neural Stem Cells Control of adult neurogenesis by programmed cell death in the mammalian brain Recent Developments and Biological Activities of N-Substituted Carbazole Derivatives: A Review Adult hippocampal neurogenesis in Parkinson's disease: impact on neuronal survival and plasticity Therapeutic neuroprotective agents for amyotrophic lateral sclerosis Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson's disease.Recent Advances in Neurogenic Small Molecules as Innovative Treatments for Neurodegenerative Diseases Lithium improves hippocampal neurogenesis, neuropathology and cognitive functions in APP mutant mice Kuwanon V inhibits proliferation, promotes cell survival and increases neurogenesis of neural stem cells Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease Investigation of the neuroprotective impact of nimodipine on Neuro2a cells by means of a surgery-like stress model Chemical approaches to stem cell biology and therapeutics Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis.Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease S 38093, a histamine H3 antagonist/inverse agonist, promotes hippocampal neurogenesis and improves context discrimination task in aged mice.Identification and optimization of an aminoalcohol-carbazole series with antimalarial properties.Hypothalamic subependymal niche: a novel site of the adult neurogenesis.From the bench to the bedside: Emerging science in Parkinson's disease, cholesterol metabolism, and neuroprotection A small molecule accelerates neuronal differentiation in the adult rat.P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage Hematopoietic, CNS and skeletal muscle stem cells as drug targets: opportunities, progress and challenges.Disc1 variation leads to specific alterations in adult neurogenesis.The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis.P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties.Hippocampal neurogenesis regulates forgetting during adulthood and infancy.Proneurogenic Group II mGluR antagonist improves learning and reduces anxiety in Alzheimer Aβ oligomer mouse.Adult Hippocampal Neurogenesis, Fear Generalization, and Stress.Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction.Chemical approaches to studying stem cell biology.P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases.Endurance factors improve hippocampal neurogenesis and spatial memory in mice Development of proneurogenic, neuroprotective small molecules.Next-generation treatments for mental disorders.The current state of the neurogenic theory of depression and anxiety Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64

P2860

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P2860

Discovery of a proneurogenic, neuroprotective chemical

http://www.wikidata.org/entity/Q24620801

description

2010 nî lūn-bûn

@nan

2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հուլիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Discovery of a proneurogenic, neuroprotective chemical

@ast

Discovery of a proneurogenic, neuroprotective chemical

@en

Discovery of a proneurogenic, neuroprotective chemical

@nl

type

label

Discovery of a proneurogenic, neuroprotective chemical

@ast

Discovery of a proneurogenic, neuroprotective chemical

@en

Discovery of a proneurogenic, neuroprotective chemical

@nl

prefLabel

Discovery of a proneurogenic, neuroprotective chemical

@ast

Discovery of a proneurogenic, neuroprotective chemical

@en

Discovery of a proneurogenic, neuroprotective chemical

@nl

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P2860

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Q24620801-1EAA7567-FF41-413F-8627-124FFF3FEC73

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P356

J.CELL.2010.06.018

P1433

P1476

Discovery of a proneurogenic, neuroprotective chemical

@en

P2093

Andrew A Pieper

http://www.w3.org/2001/XMLSchema#string

Ching-Han Shen

http://www.w3.org/2001/XMLSchema#string

Daniel J Brat

http://www.w3.org/2001/XMLSchema#string

Emanuela Capota

http://www.w3.org/2001/XMLSchema#string

Ginger L Becker

http://www.w3.org/2001/XMLSchema#string

Jacinth Naidoo

http://www.w3.org/2001/XMLSchema#string

Jeannie Zhong

http://www.w3.org/2001/XMLSchema#string

Jef De Brabander

http://www.w3.org/2001/XMLSchema#string

Jeffrey M Long

http://www.w3.org/2001/XMLSchema#string

Jenny Hsieh

http://www.w3.org/2001/XMLSchema#string

P2860

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

Behavioral and regulatory abnormalities in mice deficient in the NPAS1 and NPAS3 transcription factors.

Disruption of the neuronal PAS3 gene in a family affected with schizophrenia

Mitochondria as a target for neurotoxins and neuroprotective agents

Antihistamine agent Dimebon as a novel neuroprotector and a cognition enhancer

Transient expression of doublecortin during adult neurogenesis

Disruption of a brain transcription factor, NPAS3, is associated with schizophrenia and learning disability

Autoradiographic and histological evidence of postnatal hippocampal neurogenesis in rats

The NPAS3 gene--emerging evidence for a role in psychiatric illness

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39-51

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scholarly article

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1889899

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10.1016/J.CELL.2010.06.018

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P433

1

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142

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Shauna E Goldman

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2010-07-01T00:00:00Z

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45094053

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20603013

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2930815

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