Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial
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Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's DiseaseRationale for short course primaquine in Africa to interrupt malaria transmissionThe bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blueThe activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasitesEvidence for the contribution of the hemozoin synthesis pathway of the murine Plasmodium yoelii to the resistance to artemisinin-related drugsActivity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence "transmission blocking" assayTargeting asymptomatic malaria infections: active surveillance in control and eliminationReal-time imaging of the intracellular glutathione redox potential in the malaria parasite Plasmodium falciparumGametocytocidal screen identifies novel chemical classes with Plasmodium falciparum transmission blocking activityThe Interactions of P-Glycoprotein with Antimalarial Drugs, Including Substrate Affinity, Inhibition and RegulationA high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase-based mature gametocyte assayGlycoluril-Derived Molecular Clips are Potent and Selective Receptors for Cationic Dyes in Water.Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and eliminationCellular and molecular actions of Methylene Blue in the nervous systemAntimalarial compounds in Phase II clinical development.Effect of fluorescent dyes on in vitro-differentiated, late-stage Plasmodium falciparum gametocytes.Plasmodium drug targets outside the genetic control of the parasite.Plasmodium falciparum susceptibility to standard and potential anti-malarial drugs in Dakar, Senegal, during the 2013-2014 malaria season.Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blueImaging-based high-throughput screening assay to identify new molecules with transmission-blocking potential against Plasmodium falciparum female gamete formation.Potent Ex Vivo Activity of Naphthoquine and Methylene Blue against Drug-Resistant Clinical Isolates of Plasmodium falciparum and Plasmodium vivax.Anti-malarial drugs: how effective are they against Plasmodium falciparum gametocytes?Analyzing Thiol-Dependent Redox Networks in the Presence of Methylene Blue and Other Antimalarial Agents with RT-PCR-Supported in silico Modeling.The antimalarial activities of methylene blue and the 1,4-naphthoquinone 3-[4-(trifluoromethyl)benzyl]-menadione are not due to inhibition of the mitochondrial electron transport chain.Impact of methylene blue and atorvastatin combination therapy on the apparition of cerebral malaria in a murine model.Methylene blue induces macroautophagy through 5' adenosine monophosphate-activated protein kinase pathway to protect neurons from serum deprivation1,4-naphthoquinones and other NADPH-dependent glutathione reductase-catalyzed redox cyclers as antimalarial agentsIn vitro evaluation of imidazo[4,5-c]quinolin-2-ones as gametocytocidal antimalarial agentsMale and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs.Efficacy of proveblue (methylene blue) in an experimental cerebral malaria murine modelCytostatic versus cytocidal profiling of quinoline drug combinations via modified fixed-ratio isobologram analysis.Chemical signatures and new drug targets for gametocytocidal drug development.Plasmodium cell biology should inform strategies used in the development of antimalarial transmission-blocking drugs.Strategic use of antimalarial drugs that block falciparum malaria parasite transmission to mosquitoes to achieve local malaria elimination.Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.Efficacy and safety of the mosquitocidal drug ivermectin to prevent malaria transmission after treatment: a double-blind, randomized, clinical trial.Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages: Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes.[Role of primaquine in malaria control and elimination in French-speaking Africa].Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties.Baseline in vitro activities of the antimalarials pyronaridine and methylene blue against Plasmodium falciparum isolates from Kenya.
P2860
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P2860
Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Strong gametocytocidal effect ...... a randomised controlled trial
@ast
Strong gametocytocidal effect ...... a randomised controlled trial
@en
Strong gametocytocidal effect ...... a randomised controlled trial
@en-gb
Strong gametocytocidal effect ...... a randomised controlled trial
@nl
type
label
Strong gametocytocidal effect ...... a randomised controlled trial
@ast
Strong gametocytocidal effect ...... a randomised controlled trial
@en
Strong gametocytocidal effect ...... a randomised controlled trial
@en-gb
Strong gametocytocidal effect ...... a randomised controlled trial
@nl
altLabel
Strong Gametocytocidal Effect ...... A Randomised Controlled Trial
@en
prefLabel
Strong gametocytocidal effect ...... a randomised controlled trial
@ast
Strong gametocytocidal effect ...... a randomised controlled trial
@en
Strong gametocytocidal effect ...... a randomised controlled trial
@en-gb
Strong gametocytocidal effect ...... a randomised controlled trial
@nl
P2093
P2860
P3181
P1433
P1476
Strong gametocytocidal effect ...... a randomised controlled trial
@en
P2093
Boubacar Coulibaly
Christina Klose
Olaf Müller
Peter E Meissner
R Heiner Schirmer
Ulrich Mansmann
P2860
P3181
P356
10.1371/JOURNAL.PONE.0005318
P407
P577
2009-01-01T00:00:00Z