Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
about
Marine algae sulfated polysaccharides for tissue engineering and drug delivery approachesIn vivo binding and retention of CD4-specific DARPin 57.2 in macaquesPolyICLC Exerts Pro- and Anti-HIV Effects on the DC-T Cell Milieu In Vitro and In VivoA Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex VivoA macaque model to study vaginal HSV-2/immunodeficiency virus co-infection and the impact of HSV-2 on microbicide efficacyMobilization of HIV spread by diaphanous 2 dependent filopodia in infected dendritic cellsAn antiretroviral/zinc combination gel provides 24 hours of complete protection against vaginal SHIV infection in macaquesExposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaquesThe Intranasal Application of Zanamivir and Carrageenan Is Synergistically Active against Influenza A Virus in the Murine ModelIota-carrageenan is a potent inhibitor of influenza A virus infectionFormulation, pharmacokinetics and pharmacodynamics of topical microbicides.Semi-solid gels function as physical barriers to human immunodeficiency virus transport in vitro.Historical development of vaginal microbicides to prevent sexual transmission of HIV in women: from past failures to future hopes.Depo-Provera does not alter disease progression in SIVmac-infected female Chinese rhesus macaquesDisruption of tight junctions by cellulose sulfate facilitates HIV infection: model of microbicide safetyIn vitro and in vivo evaluation of two carrageenan-based formulations to prevent HPV acquisition.Bridging the gap between preclinical and clinical microbicide trials: blind evaluation of candidate gels in murine models of efficacy and safety.A MIV-150/zinc acetate gel inhibits SHIV-RT infection in macaque vaginal explantsShort communication: a repeated simian human immunodeficiency virus reverse transcriptase/herpes simplex virus type 2 cochallenge macaque model for the evaluation of microbicidesThe nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simian/human immunodeficiency virus infection in macaques.Topical prophylaxis for HIV prevention in women: becoming a reality.A potent combination microbicide that targets SHIV-RT, HSV-2 and HPVNon-specific microbicide product development: then and nowAn intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaquesZinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge.MIV-150/zinc acetate gel inhibits cell-associated simian-human immunodeficiency virus reverse transcriptase infection in a macaque vaginal explant model.Application and removal of polyanionic microbicide compounds enhances subsequent infection by HIV-1Update on microbicide research and development - seeking new HIV prevention tools for women.Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase.A perspective on progress and gaps in HIV prevention scienceA single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use.The nonnucleoside reverse transcription inhibitor MIV-160 delivered from an intravaginal ring, but not from a carrageenan gel, protects against simian/human immunodeficiency virus-RT Infection.Novel RNA Duplex Locks HIV-1 in a Latent State via Chromatin-mediated Transcriptional Silencing.A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivo.Topical application of entry inhibitors as "virustats" to prevent sexual transmission of HIV infection.Oligomerization of the macrophage mannose receptor enhances gp120-mediated binding of HIV-1.In Vitro Exposure to PC-1005 and Cervicovaginal Lavage Fluid from Women Vaginally Administered PC-1005 Inhibits HIV-1 and HSV-2 Infection in Human Cervical MucosaPharmacokinetics and pharmacodynamics in HIV prevention; current status and future directions: a summary of the DAIDS and BMGF sponsored think tank on pharmacokinetics (PK)/pharmacodynamics (PD) in HIV prevention.Enhancement of human immunodeficiency virus type 1 replication is not intrinsic to all polyanion-based microbicides.The differential binding and activity of PRO 2000 against diverse HIV-1 envelopes.
P2860
Q27012747-C59CDC13-D9C5-4972-81BC-1EAA0B228921Q27320871-882F3C5C-345A-4D5A-8C34-82AD00D13325Q27324710-5076DE5A-34BD-447D-953E-D46D80FE95B2Q27334384-63412A93-2AFB-4B5B-BB82-06A2D64B519EQ27335068-5DA750E8-09A5-486A-8D0D-18EBE8B5CC46Q27345158-A7BD8795-79D4-4E09-ADDD-57DB03CCCD85Q27438093-4884F63B-D5A1-4378-BCEC-16053A7BF4FFQ28540200-1331096B-85F1-419B-A84B-003952B65038Q28547982-1C44F9A4-90DB-4918-9ED4-B18F30B05043Q28744254-DA3DC63A-076B-4959-BFFF-6116A642F204Q30412592-C47017E5-732F-4AB2-A2CC-D8F5B025E716Q30499386-8039AA86-E9A9-446E-BACB-EB321C67B166Q33821090-CBD0E06F-3627-4016-AB52-844345099C95Q33827820-5C77D0E7-A538-407C-A04A-098256A02845Q33880947-89F6632A-FB1C-4C10-8AFC-C76D2358A60DQ33978803-BD2627D0-785A-4005-BE12-D9B72A7D65B9Q34078011-8A28B51E-66E5-43EA-AFEE-DF70DC17A001Q34258224-8BC3B04D-93A2-46F8-8DC5-31F3C20A7249Q34399737-CA83D1A5-84D8-4469-B4A8-865E3ECD17B9Q34982693-F3AE8FCE-7EF4-4B54-8A7D-C795228AE861Q35031133-A9100395-9382-4566-8199-70D380ED1B8DQ35150470-AAF8BCBF-7D6D-4F61-8B4B-07E5624BEA33Q35345283-331E3221-9C69-4A31-9A25-32EEAAF3EB3FQ35345363-EF40014C-B93D-4CC4-9451-749ACEFC365AQ35666495-2B5D10E4-FDD1-4EFD-B41F-D2A2F0A2B1D6Q35746218-C0937AA1-939E-4C35-B234-7BA4F0205C16Q35808786-66038E56-D261-4778-A4EB-792EE33F21DEQ35958928-824F0BC5-417F-4CDB-8784-A37CAB31D62EQ36290753-FDEA8D45-FE73-4F50-AC7A-E22E821C7391Q36358897-3D3A830F-954C-427F-8526-71A95DC1F7E0Q36359120-12A6CD6E-8B9E-48AA-BECE-5C233A84E77CQ36359133-46D1A2A6-6DEC-4C2C-ADB3-9604F76D8F91Q36939741-2112B7E5-1BCE-4C9A-9A5D-22FE60D71394Q37036620-141553B2-1653-4B55-A86A-EF1DA36158DAQ37088591-238E2E15-3554-4E57-A278-992C985745D4Q37160836-98DC911E-22B0-4D7C-B18A-BA1A06E9B223Q37203838-2473FCFB-AD3F-418E-BCB9-8824E56D6FBCQ37258271-F27BCB06-1E2F-4591-B3FA-139E2D61DF10Q37274721-12579804-EA4F-46CD-B381-C9692E3CC2B4Q37283747-C01EF0F6-A5F3-4F97-AA56-1D0D308A4D84
P2860
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
description
2008 nî lūn-bûn
@nan
2008 թուականին հրատարակուած գիտական յօդուած
@hyw
2008 թվականին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@ast
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@en
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@en-gb
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@nl
type
label
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@ast
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@en
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@en-gb
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@nl
altLabel
Efficacy of Carraguard®-Based Microbicides In Vivo Despite Variable In Vitro Activity
@en
prefLabel
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@ast
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@en
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@en-gb
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@nl
P2093
P2860
P3181
P1433
P1476
Efficacy of Carraguard-based microbicides in vivo despite variable in vitro activity
@en
P2093
Aaron Teitelbaum
Agegnehu Gettie
Anne Chudolij
James Blanchard
Jeffrey D Lifson
Jessica Kenney
Julian W Bess
Melissa Robbiani
Meropi Aravantinou
P2860
P3181
P356
10.1371/JOURNAL.PONE.0003162
P407
P577
2008-09-08T00:00:00Z