Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques
about
A Novel Microbicide/Contraceptive Intravaginal Ring Protects Macaque Genital Mucosa against SHIV-RT Infection Ex VivoHistorical development of vaginal microbicides to prevent sexual transmission of HIV in women: from past failures to future hopes.The emerging profile of cross-resistance among the nonnucleoside HIV-1 reverse transcriptase inhibitors.Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase.A novel intravaginal ring to prevent HIV-1, HSV-2, HPV, and unintended pregnancyMultipurpose Prevention Approaches with Antiretroviral-Based FormulationsIn Vitro Exposure to PC-1005 and Cervicovaginal Lavage Fluid from Women Vaginally Administered PC-1005 Inhibits HIV-1 and HSV-2 Infection in Human Cervical MucosaDerivation and Characterization of Pathogenic Transmitted/Founder Molecular Clones from Simian Immunodeficiency Virus SIVsmE660 and SIVmac251 following Mucosal Infection.First-in-Human Trial of MIV-150 and Zinc Acetate Coformulated in a Carrageenan Gel: Safety, Pharmacokinetics, Acceptability, Adherence, and Pharmacodynamics.MIV-150 and zinc acetate combination provides potent and broad activity against HIV-1.An intravaginal ring that releases three antiviral agents and a contraceptive blocks SHIV-RT infection, reduces HSV-2 shedding, and suppresses hormonal cycling in rhesus macaques.In Vitro Cross-Resistance Profiles of Rilpivirine, Dapivirine, and MIV-150, Nonnucleoside Reverse Transcriptase Inhibitor Microbicides in Clinical Development for the Prevention of HIV-1 Infection.
P2860
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P2860
Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques
description
2014 nî lūn-bûn
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2014 թուականին հրատարակուած գիտական յօդուած
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
@zh-mo
2014年論文
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2014年论文
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name
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@ast
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@en
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@nl
type
label
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@ast
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@en
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@nl
prefLabel
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@ast
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@en
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@nl
P2093
P2860
P3181
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P1476
Exposure to MIV-150 from a hig ...... IV-RT infected rhesus macaques
@en
P2093
Agegnehu Gettie
Aixa Rodriguez
Brooke Grasperge
Ciby J Abraham
James Blanchard
Jeffrey D Lifson
José A Fernández-Romero
Larisa Kizima
Melissa Robbiani
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0089300
P407
P577
2014-01-01T00:00:00Z