A family of cAMP-binding proteins that directly activate Rap1
about
Structure-guided design of selective Epac1 and Epac2 agonistsAn autism-associated variant of Epac2 reveals a role for Ras/Epac2 signaling in controlling basal dendrite maintenance in miceCharacterization of GFR, a novel guanine nucleotide exchange factor for Rap1RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humansPDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3Mechanism of regulation of the Epac family of cAMP-dependent RapGEFsIdentification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interactionEstrogen increases smooth muscle expression of alpha2C-adrenoceptors and cold-induced constriction of cutaneous arteriesRA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activationRapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cellsThe RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membraneExendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factorsThe Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeletonDirect binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activationThe protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways.Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1ARGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphaoGlucagon-like peptide-1 mobilizes intracellular Ca2+ and stimulates mitochondrial ATP synthesis in pancreatic MIN6 beta-cellsResveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterasesEpac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cellDesign of versatile biochemical switches that respond to amplitude, duration, and spatial cuesRole of Rap1B and tumor suppressor PTEN in the negative regulation of lysophosphatidic acid--induced migration by isoproterenol in glioma cellsThe junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilinExchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neuronsThe M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytesMechanisms of action of glucagon-like peptide 1 in the pancreasRole of EPAC in cAMP-Mediated Actions in Adrenocortical CellsMolecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling UnitsThe cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory DiseasesTargeting protein-protein interactions in complexes organized by A kinase anchoring proteinsCardiac cAMP: production, hydrolysis, modulation and detectionDopamine Receptors and NeurodegenerationThe genetically encoded tool set for investigating cAMP: more than the sum of its partsRegulation of small GTPases by GEFs, GAPs, and GDIsRole of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiologyInvestigation of cAMP microdomains as a path to novel cancer diagnosticsCRIS-a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bendingStructure of the small G protein Rap2 in a non-catalytic complex with GTPStructural Analyses of a Constitutively Active Mutant of Exchange Protein Directly Activated by cAMP
P2860
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P2860
A family of cAMP-binding proteins that directly activate Rap1
description
1998 nî lūn-bûn
@nan
1998 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
A family of cAMP-binding proteins that directly activate Rap1
@ast
A family of cAMP-binding proteins that directly activate Rap1
@en
A family of cAMP-binding proteins that directly activate Rap1
@en-gb
A family of cAMP-binding proteins that directly activate Rap1
@nl
type
label
A family of cAMP-binding proteins that directly activate Rap1
@ast
A family of cAMP-binding proteins that directly activate Rap1
@en
A family of cAMP-binding proteins that directly activate Rap1
@en-gb
A family of cAMP-binding proteins that directly activate Rap1
@nl
prefLabel
A family of cAMP-binding proteins that directly activate Rap1
@ast
A family of cAMP-binding proteins that directly activate Rap1
@en
A family of cAMP-binding proteins that directly activate Rap1
@en-gb
A family of cAMP-binding proteins that directly activate Rap1
@nl
P2093
P2860
P921
P3181
P1433
P1476
A family of cAMP-binding proteins that directly activate Rap1
@en
P2093
A M Graybiel
D E Housman
G M Springett
H Kawasaki
N Mochizuki
P2860
P304
P3181
P356
10.1126/SCIENCE.282.5397.2275
P407
P577
1998-12-01T00:00:00Z