Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux

Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux

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http://www.wikidata.org/entity/Q28484950
Analytical Characterization of Methyl-β-Cyclodextrin for Pharmacological Activity to Reduce Lysosomal Cholesterol Accumulation in Niemann-Pick Disease Type C1 Cells.Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrinMetabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with TemozolomideInhibition of miR-29 has a significant lipid-lowering benefit through suppression of lipogenic programs in liver.Histone deacetylase inhibitors modulate KATP subunit transcription in HL-1 cardiomyocytes through effects on cholesterol homeostasis.Neuronal gene repression in Niemann-Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway.Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage.Activation of PKC triggers rescue of NPC1 patient specific iPSC derived glial cells from gliosis.Altered Cholesterol Intracellular Trafficking and the Development of Pathological Hallmarks of Sporadic AD.Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1).Normalization of Hepatic Homeostasis in the Npc1nmf164 Mouse Model of Niemann-Pick Type C Disease Treated with the Histone Deacetylase Inhibitor Vorinostat.Epigenetic therapies - a new direction in clinical medicine.
P2860

Histone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and efflux

Item
http://www.wikidata.org/entity/Q28484950
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@ast
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@nl
type
label
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@ast
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@nl
prefLabel
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@ast
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@nl
P1433
P1476
P2093
P2860
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P356
P407
P433
P478
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P5875
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P932
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P1476
Histone deacetylase inhibition ...... l synthesis, uptake and efflux
@en
P2093
P2860
P304
P31
P356
10.1371/JOURNAL.PONE.0053394
P407
P433
P478
P50
P577
P5875
P698
P932