Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase
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Dimerization and release of molecular chaperone inhibition facilitate activation of eukaryotic initiation factor-2 kinase in response to endoplasmic reticulum stressSignaling by target of rapamycin proteins in cell growth controlEvidence that the dephosphorylation of Ser(535) in the epsilon-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulinHepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathwayIdentification of domains and residues within the epsilon subunit of eukaryotic translation initiation factor 2B (eIF2Bepsilon) required for guanine nucleotide exchange reveals a novel activation function promoted by eIF2B complex formationAssociation of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activationThe roles of nitric oxide synthase and eIF2alpha kinases in regulation of cell cycle upon UVB-irradiationNrf2 is a direct PERK substrate and effector of PERK-dependent cell survivalIfkA, a presumptive eIF2 alpha kinase of Dictyostelium, is required for proper timing of aggregation and regulation of mound sizePulmonary capillary hemangiomatosis: a focus on the EIF2AK4 mutation in onset and pathogenesisConserved and plant-unique strategies for overcoming endoplasmic reticulum stressChanges in translational control after pro-apoptotic stressNutrient-sensing mechanisms across evolutionPhosphorylation of initiation factor eIF2 in response to stress conditions is mediated by acidic ribosomal P1/P2 proteins in Saccharomyces cerevisiae.Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.IRF3 and IRF7 phosphorylation in virus-infected cells does not require double-stranded RNA-dependent protein kinase R or Ikappa B kinase but is blocked by Vaccinia virus E3L proteinEnhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKRSalicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent mannerGlucose exerts a permissive effect on the regulation of the initiation factor 4E binding protein 4E-BP1Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiencyThe PERK eukaryotic initiation factor 2 alpha kinase is required for the development of the skeletal system, postnatal growth, and the function and viability of the pancreasFeedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alphaDeficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed ratsRegulatory proteins of eukaryotic initiation factor 2-alpha subunit (eIF2 alpha) phosphatase, under ischemic reperfusion and toleranceTranslation mediated by the internal ribosome entry site of the cat-1 mRNA is regulated by glucose availability in a PERK kinase-dependent mannerAntiviral effect of the mammalian translation initiation factor 2alpha kinase GCN2 against RNA virusesTranslational control of hippocampal synaptic plasticity and memory by the eIF2alpha kinase GCN2Heme-regulated eIF2alpha kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and beta-thalassemiaIMPACT is a developmentally regulated protein in neurons that opposes the eukaryotic initiation factor 2α kinase GCN2 in the modulation of neurite outgrowthTranslational control by eIF2α kinases in long-lasting synaptic plasticity and long-term memory.Amino acids regulate transgene expression in MDCK cells.Decreased ATF4 expression as a mechanism of acquired resistance to long-term amino acid limitation in cancer cellsA PKR-like eukaryotic initiation factor 2alpha kinase from zebrafish contains Z-DNA binding domains instead of dsRNA binding domainsRegulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathwayGcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress.Glucose limitation induces GCN4 translation by activation of Gcn2 protein kinase.Translation initiation control by heme-regulated eukaryotic initiation factor 2alpha kinase in erythroid cells under cytoplasmic stresses.P58IPK, a novel endoplasmic reticulum stress-inducible protein and potential negative regulator of eIF2alpha signaling.ERG-APLNR axis controls pulmonary venule endothelial proliferation in pulmonary veno-occlusive disease.The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice.
P2860
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P2860
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase
description
1999 nî lūn-bûn
@nan
1999 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
name
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@ast
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@en
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@en-gb
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@nl
type
label
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@ast
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@en
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@en-gb
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@nl
prefLabel
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@ast
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@en
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@en-gb
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@nl
P2860
P3181
P1433
P1476
Characterization of a mammalia ...... nitiation factor 2alpha kinase
@en
P2093
P2860
P304
P3181
P356
10.1046/J.1432-1327.1999.00780.X
P407
P577
1999-10-01T00:00:00Z