Neuroligins and neurexins link synaptic function to cognitive disease
about
Gephyrin, the enigmatic organizer at GABAergic synapsesBasic mechanisms for recognition and transport of synaptic cargosAlterations of GABAergic signaling in autism spectrum disordersMeta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairmentsTruncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophreniaRare deletions at the neurexin 3 locus in autism spectrum disorderNeuroligin-1-dependent competition regulates cortical synaptogenesis and synapse numberThe novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organizationA neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum exportCNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in DrosophilaStructural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and FynMouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments.Fbxo45, a novel ubiquitin ligase, regulates synaptic activityAutistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor functionStructural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell AdhesionInvestigating synapse formation and function using human pluripotent stem cell-derived neuronsCalsyntenins function as synaptogenic adhesion molecules in concert with neurexinsIntellectual disability associated with a homozygous missense mutation in THOC6Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses.Actin in dendritic spines: connecting dynamics to functionFunction directs form of neuronal architectureActivity-dependent regulation of synapses by retrograde messengersSAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1Emerging pharmacotherapies for neurodevelopmental disordersLRRTMs and neuroligins bind neurexins with a differential code to cooperate in glutamate synapse developmentAutism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signalingQuantitative biology of single neuronsMechanisms of synapse and dendrite maintenance and their disruption in psychiatric and neurodegenerative disordersNeurexins and neuroligins: recent insights from invertebratesThe structure of neurexin 1α reveals features promoting a role as synaptic organizerNeurexin 1 (NRXN1) deletions in schizophreniaβ-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid SignalingSingle-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin IsoformsPathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor traffickingDistinct circuit-dependent functions of presynaptic neurexin-3 at GABAergic and glutamatergic synapses.Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.Direct visualization of trans-synaptic neurexin-neuroligin interactions during synapse formationNeurotransmitter release: the last millisecond in the life of a synaptic vesicleLeucine-rich repeat transmembrane proteins are essential for maintenance of long-term potentiation
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Neuroligins and neurexins link synaptic function to cognitive disease
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Neuroligins and neurexins link synaptic function to cognitive disease
@ast
Neuroligins and neurexins link synaptic function to cognitive disease
@en
Neuroligins and neurexins link synaptic function to cognitive disease
@en-gb
Neuroligins and neurexins link synaptic function to cognitive disease
@nl
type
label
Neuroligins and neurexins link synaptic function to cognitive disease
@ast
Neuroligins and neurexins link synaptic function to cognitive disease
@en
Neuroligins and neurexins link synaptic function to cognitive disease
@en-gb
Neuroligins and neurexins link synaptic function to cognitive disease
@nl
prefLabel
Neuroligins and neurexins link synaptic function to cognitive disease
@ast
Neuroligins and neurexins link synaptic function to cognitive disease
@en
Neuroligins and neurexins link synaptic function to cognitive disease
@en-gb
Neuroligins and neurexins link synaptic function to cognitive disease
@nl
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Neuroligins and neurexins link synaptic function to cognitive disease
@en
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10.1038/NATURE07456
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2008-10-16T00:00:00Z
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1029519662