Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
about
Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairmentsClinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Striatal Circuits as a Common Node for Autism PathophysiologyNew Therapeutic Options for Autism Spectrum Disorder: Experimental EvidencesBehavioral phenotypes of genetic mouse models of autism.Modeling psychiatric disorders for developing effective treatmentsUnderstanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patientsSynaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.Brain-specific transcriptional regulator T-brain-1 controls brain wiring and neuronal activity in autism spectrum disordersTherapeutic approaches for shankopathiesDeveloping Medications Targeting Glutamatergic Dysfunction in Autism: Progress to DateActinin-4 Governs Dendritic Spine Dynamics and Promotes Their Remodeling by Metabotropic Glutamate Receptors.Coronin 1 regulates cognition and behavior through modulation of cAMP/protein kinase A signalingAltered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice.Genetic aspects of autism spectrum disorders: insights from animal modelsActin-Dependent Alterations of Dendritic Spine Morphology in ShankopathiesAdvancing the understanding of autism disease mechanisms through geneticsNeuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorderNeurobiology of social behavior abnormalities in autism and Williams syndromeSynaptopathies: synaptic dysfunction in neurological disorders - A review from students to studentsCommon mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disordersHuman variants in the neuronal basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) transcription factor complex NPAS4/ARNT2 disrupt functionAutism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficitsTranslational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.Shank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanismTbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormalityAutism-related deficits via dysregulated eIF4E-dependent translational control.Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication.ASD-relevant Animal Models of the Foxp Family of Transcription FactorsJAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.SHANK proteins: roles at the synapse and in autism spectrum disorder.The ADHD-linked human dopamine D4 receptor variant D4.7 induces over-suppression of NMDA receptor function in prefrontal cortex.Whole-genome sequencing in multiplex families with psychoses reveals mutations in the SHANK2 and SMARCA1 genes segregating with illness.Synaptic proteins and receptors defects in autism spectrum disordersProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function.Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.The Neurobiological Basis for Social Affiliation in Autism Spectrum Disorder and Schizophrenia.Deficits in social behavioral tests in a mouse model of alternating hemiplegia of childhood.
P2860
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P2860
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function
description
2012 nî lūn-bûn
@nan
2012 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Autistic-like social behaviour ...... storing NMDA receptor function
@ast
Autistic-like social behaviour ...... storing NMDA receptor function
@en
Autistic-like social behaviour ...... storing NMDA receptor function
@en-gb
Autistic-like social behaviour ...... storing NMDA receptor function
@nl
type
label
Autistic-like social behaviour ...... storing NMDA receptor function
@ast
Autistic-like social behaviour ...... storing NMDA receptor function
@en
Autistic-like social behaviour ...... storing NMDA receptor function
@en-gb
Autistic-like social behaviour ...... storing NMDA receptor function
@nl
prefLabel
Autistic-like social behaviour ...... storing NMDA receptor function
@ast
Autistic-like social behaviour ...... storing NMDA receptor function
@en
Autistic-like social behaviour ...... storing NMDA receptor function
@en-gb
Autistic-like social behaviour ...... storing NMDA receptor function
@nl
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P2860
P50
P921
P3181
P356
P1433
P1476
Autistic-like social behaviour ...... storing NMDA receptor function
@en
P2093
Bong-Kiun Kaang
Changuk Chung
Daesoo Kim
Eun Suk Jung
Eunjoon Kim
Hye-Ryeon Lee
Hyejung Won
Jung-Soo Lee
Kyungmin Lee
Sae-Geun Park
P2860
P2888
P3181
P356
10.1038/NATURE11208
P407
P577
2012-06-14T00:00:00Z
P5875
P6179
1007823118