The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing
about
Bridging the synaptic gap: neuroligins and neurexin I in Apis melliferaNeuropathology and animal models of autism: genetic and environmental factorsAutistic phenotypes and genetic testing: state-of-the-art for the clinical geneticistAdvances in autism genetics: on the threshold of a new neurobiologyNeuroligins and neurexins link synaptic function to cognitive diseaseDissection of synapse induction by neuroligins: effect of a neuroligin mutation associated with autismStructural analysis of the synaptic protein neuroligin and its beta-neurexin complex: determinants for folding and cell adhesionLinkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility geneA neuroligin-4 missense mutation associated with autism impairs neuroligin-4 folding and endoplasmic reticulum exportStructural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.Investigating synapse formation and function using human pluripotent stem cell-derived neuronsA neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in micealpha-Latrotoxin and its receptorsDisruption of neurexin 1 associated with autism spectrum disorder.Mutational analysis of the neurexin/neuroligin complex reveals essential and regulatory componentsNeurexin-neuroligin signaling in synapse developmentA genetic study of autism in Costa Rica: multiple variables affecting IQ scores observed in a preliminary sample of autistic casesNew players tip the scales in the balance between excitatory and inhibitory synapses.Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampusNeuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validationNeuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior.Clinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Regulation of synaptic nlg-1/neuroligin abundance by the skn-1/Nrf stress response pathway protects against oxidative stressA neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in miceStructural basis for synaptic adhesion mediated by neuroligin-neurexin interactionsCrystal structure of the extracellular cholinesterase-like domain from neuroligin-2The Crystal Structure of the α-Neurexin-1 Extracellular Region Reveals a Hinge Point for Mediating Synaptic Adhesion and FunctionGenetic aspects of autism spectrum disorders: insights from animal modelsThe interplay between synaptic activity and neuroligin function in the CNSCommon mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disordersNeurexins and neuroligins: synapses look out of the nervous systemNeuronal connectivity as a convergent target of gene × environment interactions that confer risk for Autism Spectrum DisordersRestoration of proper trafficking to the cell surface for membrane proteins harboring cysteine mutationsExpression of neurexin, neuroligin, and their cytoplasmic binding partners in the pancreatic beta-cells and the involvement of neuroligin in insulin secretionNGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formationA mutation linked with autism reveals a common mechanism of endoplasmic reticulum retention for the alpha,beta-hydrolase fold protein familyUsing Gene Ontology to describe the role of the neurexin-neuroligin-SHANK complex in human, mouse and rat and its relevance to autismHomodimerization and isoform-specific heterodimerization of neuroligins
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P2860
The Arg451Cys-neuroligin-3 mutation associated with autism reveals a defect in protein processing
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@ast
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@en
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@en-gb
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@nl
type
label
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@ast
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@en
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@en-gb
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@nl
prefLabel
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@ast
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@en
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@en-gb
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@nl
P2093
P921
P3181
P1476
The Arg451Cys-neuroligin-3 mut ...... a defect in protein processing
@en
P2093
Antonella De Jaco
Davide Comoletti
Guido Gaietta
Igor Tsigelny
Lori L Jennings
Mark H Ellisman
Palmer Taylor
Robyn E Flynn
P304
P3181
P356
10.1523/JNEUROSCI.0468-04.2004
P407
P577
2004-05-19T00:00:00Z