Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
about
Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assemblyThymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNALesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNAStructural analysis of an Escherichia coli endonuclease VIII covalent reaction intermediate.Mutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylaseUracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanismsAccessing DNA damage in chromatin: Preparing the chromatin landscape for base excision repairSolution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase IEnzymatic capture of an extrahelical thymine in the search for uracil in DNADNA apurinic-apyrimidinic site binding and excision by endonuclease IVA New Protein Architecture for Processing Alkylation Damaged DNA: The Crystal Structure of DNA Glycosylase AlkDFlipping of alkylated DNA damage bridges base and nucleotide excision repairTransition state analogues in structures of ricin and saporin ribosome-inactivating proteinsStructure of uracil-DNAN-glycosylase (UNG) fromVibrio cholerae: mapping temperature adaptation through structural and mutational analysisStructure of uracil-DNA glycosylase fromMycobacterium tuberculosis: insights into interactions with ligandsAn unprecedented nucleic acid capture mechanism for excision of DNA damageAnalysis of substrate specificity of Schizosaccharomyces pombe Mag1 alkylpurine DNA glycosylaseAlkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation- interactionsUV damage endonuclease employs a novel dual-dinucleotide flipping mechanism to recognize different DNA lesionsCrystal structure and functional insights into uracil-DNA glycosylase inhibition by phage 29 DNA mimic protein p56Structure of the uracil complex ofVaccinia virusuracil DNA glycosylaseStructural and biophysical analysis of interactions between cod and human uracil-DNAN-glycosylase (UNG) and UNG inhibitor (Ugi)Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residuesUracil-DNA glycosylase acts by substrate autocatalysisBase excision and DNA binding activities of human alkyladenine DNA glycosylase are sensitive to the base paired with a lesionUracil-DNA glycosylase: Structural, thermodynamic and kinetic aspects of lesion search and recognitionNontarget DNA binding shapes the dynamic landscape for enzymatic recognition of DNA damage.Mutational analysis of arginine 276 in the leucine-loop of human uracil-DNA glycosylase.Dynamic opening of DNA during the enzymatic search for a damaged base.Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNAUracil DNA glycosylase: revisiting substrate-assisted catalysis by DNA phosphate anions.Recent progress in the biology, chemistry and structural biology of DNA glycosylases.Mimicking damaged DNA with a small molecule inhibitor of human UNG2.Uracil DNA glycosylase activity on nucleosomal DNA depends on rotational orientation of targetsPredicting protein-DNA interactions by full search computational docking.Microfluidic Channels on Nanopatterned Substrates: Monitoring Protein Binding to Lipid Bilayers with Surface-Enhanced Raman Spectroscopy.Vpr-host interactions during HIV-1 viral life cycle.AdoMet-dependent methylation, DNA methyltransferases and base flipping.Base excision repair of DNA in mammalian cells.XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase.
P2860
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P2860
Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
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name
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@ast
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@en
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@en-gb
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@nl
type
label
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@ast
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@en
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@en-gb
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@nl
prefLabel
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@ast
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@en
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@en-gb
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@nl
P2093
P2860
P921
P3181
P356
P1476
Uracil-DNA glycosylase-DNA sub ...... upled stereoelectronic effects
@en
P2093
G M Blackburn
J A Tainer
S S Parikh
P2860
P304
P3181
P356
10.1073/PNAS.97.10.5083
P407
P577
2000-05-09T00:00:00Z