Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor
about
Discovery of microvascular miRNAs using public gene expression data: miR-145 is expressed in pericytes and is a regulator of Fli1Tescalcin is an essential factor in megakaryocytic differentiation associated with Ets family gene expressionFunctional cross-antagonism between transcription factors FLI-1 and EKLFFLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopeniaEts-1 and Ets-2 regulate the expression of microRNA-126 in endothelial cellsERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specificationEts1-related protein is a key regulator of vasculogenesis in zebrafishThe "Ets" factor: vessel formation in zebrafish--the missing link?The ETS Factor, ETV2: a Master Regulator for Vascular Endothelial Cell DevelopmentGene-environment interactions in severe intraventricular hemorrhage of preterm neonatesPluripotent stem cells reveal the developmental biology of human megakaryocytes and provide a source of platelets for clinical applicationCloning and analysis of the thrombopoietin-induced megakaryocyte-specific glycoprotein VI promoter and its regulation by GATA-1, Fli-1, and Sp1Transforming growth factor-beta regulates DNA binding activity of transcription factor Fli1 by p300/CREB-binding protein-associated factor-dependent acetylationMaturation stage-specific regulation of megakaryopoiesis by pointed-domain Ets proteinsTranscriptional repressor erf determines extraembryonic ectoderm differentiationEts factors and a newly identified polymorphism regulate Fli1 promoter activity in lymphocytesDosage-dependent requirement for mouse Vezf1 in vascular system developmentETS family protein ETV2 is required for initiation of the endothelial lineage but not the hematopoietic lineage in the Xenopus embryoETS2 and ERG promote megakaryopoiesis and synergize with alterations in GATA-1 to immortalize hematopoietic progenitor cellsOverexpression of Fli-1 in astrocytoma is associated with poor prognosis.Transcriptional control of megakaryocyte development.Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis.Cellular visualization of macrophage pyroptosis and interleukin-1β release in a viral hemorrhagic infection in zebrafish larvaeA clinical and molecular study of a Bedouin family with dysmegakaryopoiesis, mild anemia, and neutropenia cured by bone marrow transplantation.Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.Deletion of ETS-1, a gene in the Jacobsen syndrome critical region, causes ventricular septal defects and abnormal ventricular morphology in mice.MegakaryopoiesisThrombocytopenia in mice lacking the carboxy-terminal regulatory domain of the Ets transcription factor Fli1.Clonal chromosome anomalies affecting FLI1 mimic inherited thrombocytopenia of the Paris-Trousseau type.Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate.Identification of nuclear import and export signals within Fli-1: roles of the nuclear import signals in Fli-1-dependent activation of megakaryocyte-specific promoters.A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specificationEndothelial Fli1 deficiency impairs vascular homeostasis: a role in scleroderma vasculopathy.Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation.Fli1 acts downstream of Etv2 to govern cell survival and vascular homeostasis via positive autoregulation.Oncogenic Fli-1 is a potential prognostic marker for the progression of epithelial ovarian cancer.Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineagesEts and retroviruses - transduction and activation of members of the Ets oncogene family in viral oncogenesis.The role of Fli-1 in normal cell function and malignant transformation.Ets target genes: past, present and future.
P2860
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P2860
Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor
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2000 nî lūn-bûn
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2000 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
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2000 թվականի օգոստոսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@ast
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@en
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@en-gb
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@nl
type
label
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@ast
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@en
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@en-gb
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@nl
prefLabel
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@ast
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@en
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@en-gb
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@nl
P2093
P2860
P921
P3181
P1476
Hemorrhage, impaired hematopoi ...... the Fli1 transcription factor
@en
P2093
D D Spyropoulos
D K Watson
K R Lavenburg
P2860
P304
P3181
P356
10.1128/MCB.20.15.5643-5652.2000
P407
P577
2000-08-01T00:00:00Z