Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1
about
SOD1 and amyotrophic lateral sclerosis: mutations and oligomerizationCharcot-Marie-Tooth-linked mutant GARS is toxic to peripheral neurons independent of wild-type GARS levelsImpairment of mitochondrial calcium handling in a mtSOD1 cell culture model of motoneuron diseaseDysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseasesDifferent human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in miceEvaluation of occupational exposure to magnetic fields and motor neuron disease mortality in a population-based cohortMutation of SOD1 in ALS: a gain of a loss of functionGlial cells as intrinsic components of non-cell-autonomous neurodegenerative diseaseStructures of the G85R variant of SOD1 in familial amyotrophic lateral sclerosisSubcellular localisation, secretion, and post-translational processing of normal cochlin, and of mutants causing the sensorineural deafness and vestibular disorder, DFNA9Misfolded CuZnSOD and amyotrophic lateral sclerosisALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomesUbiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in MiceAdeno Associated Viral Vector Delivered RNAi for Gene Therapy of SOD1 Amyotrophic Lateral SclerosisThere has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALSIs Modulation of Oxidative Stress an Answer? The State of the Art of Redox Therapeutic Actions in Neurodegenerative DiseasesImpaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron DegenerationDysregulation of glutathione homeostasis in neurodegenerative diseasesRisk factors for amyotrophic lateral sclerosisInduced pluripotent stem cells from ALS patients for disease modelingA Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanismLoss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal traffickingNeuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?Spreading of pathology in neurodegenerative diseases: a focus on human studiesPrion-like Mechanism in Amyotrophic Lateral Sclerosis: are Protein Aggregates the Key?Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosisHohenheim consensus workshop: copperAlsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutantsThe complex molecular biology of amyotrophic lateral sclerosis (ALS)The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosisMechanisms of neurodegeneration in amyotrophic lateral sclerosisTDP-43 identified from a genome wide RNAi screen for SOD1 regulatorsLate onset of motor neurons in mice overexpressing wild-type peripherinAltered aggregation properties of mutant gamma-crystallins cause inherited cataractHindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctionsScreening of Drugs Inhibiting In vitro Oligomerization of Cu/Zn-Superoxide Dismutase with a Mutation Causing Amyotrophic Lateral SclerosisSolid-state NMR studies of metal-free SOD1 fibrillar structures.Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.Accelerated s-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper,zinc-superoxide dismutase.Enhanced tethered-flight duration and locomotor activity by overexpression of the human gene SOD1 in Drosophila motorneurons
P2860
Q21090100-B9C53515-B080-4AE0-B8BB-4FD2C4F6B832Q21144936-A56BEBB2-ADBF-4AB4-83A9-B66B6FD5C269Q21262978-F7013B87-2F17-4C59-B6AB-27954DB08E67Q21285051-AC9F38DB-8FC3-40EA-869F-148AE3874327Q21560962-42DCDC7F-AD80-4B1C-9ED7-EF4A63229F35Q23916750-3B4E66CA-F9B2-4C77-8196-F877919143F1Q24305971-287DB6AA-D653-4124-9605-DAFE2628FF79Q24621854-7C42CBA5-4AA8-455D-826A-4D5D840D5C01Q24644037-B17E5D56-22EA-4B3B-8E3B-C5FC6F02346DQ24676750-F8A7EF2A-04DE-47A4-BDFB-572A7E72EBB4Q24683677-2516334B-B180-473A-A25F-3343F02E4D3FQ24792140-E4AABC7A-E271-4591-8A6D-DED6F1167E60Q26269823-B9F2DA12-20D6-4A95-A1C2-2BBE00A46B02Q26741129-FD10A8C6-D73E-412F-82BB-7D06667CE4D2Q26750577-46FC2910-F8D2-4BB5-8CAD-AF5C59AB28B8Q26765787-AAF3C571-BC5C-4AA7-BB43-05DFBCDD1555Q26766040-6ACCF560-D018-4796-8B64-ADD19ED955A0Q26822726-A0D2E6F1-3117-441D-9694-B40BE2B8ECC8Q26827642-62DC5E62-8AC3-48CC-95FD-86A5CB9B2F12Q27000647-202DE9CF-BC4F-442B-817E-B4CEF7722AE8Q27301268-EB5B6254-0D0E-400E-870A-334D35D040CDQ27332255-03DFA5B3-9087-4584-849D-620C920DDA4CQ28070156-0A518F9E-CDFB-4C77-BE76-87F492CA381DQ28082279-68C9F4CB-AB23-4A1A-BBDC-0D4882489E9DQ28087798-C7E8ACD6-51C0-4CB7-B8B0-F3CEFC8F2316Q28115951-943F9473-51AA-4688-94AA-56E7CDC238F0Q28200851-C41D91BC-BE6E-4DC6-A0A3-584A60DBE2CCQ28245736-5BA40B91-CCAC-4133-B110-83266BD5BA7FQ28263899-10CCABD8-CB80-4984-880E-B6D211927CC5Q28287224-07CD5717-AE61-4A6D-BBDA-7BEE4F49ECD1Q28365454-BCCD3384-888D-4058-86FD-9463D1696CE9Q28482611-79444870-391E-4D34-A354-366105F0499CQ28513274-6D24AE4D-D372-4742-A1D4-8A299C36C2D8Q28589540-241F518D-B650-4F6B-B8EB-62EA9D68E022Q28591272-BE3DAA52-42E8-4E69-B2A5-9615B8340FAFQ28831086-21C4212C-4827-4F33-9F20-4F0FB19A5210Q30153414-D4066689-DE1A-458B-A116-594D7ECB14DFQ30155471-8FA5434E-30C4-4B9C-9B47-BC638805DB73Q30307777-B9296B34-8B84-4354-BD52-3AC78886999DQ30411883-DBE79185-2715-4876-A781-EA88B234843B
P2860
Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@ast
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@en
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@en-gb
type
label
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@ast
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@en
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@en-gb
prefLabel
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@ast
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@en
Aggregation and Motor Neuron T ...... ndependent from Wild-Type SOD1
@en-gb
P2093
P3181
P1433
P1476
Aggregation and motor neuron t ...... ndependent from wild-type SOD1
@en
P2093
A G Reaume
K L Anderson
L I Bruijn
M K Houseweart
S D Anderson
P304
P3181
P356
10.1126/SCIENCE.281.5384.1851
P407
P577
1998-09-01T00:00:00Z