Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1 - Test2 - elhamkhani - TriplyDB

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

http://www.wikidata.org/entity/Q22299419

about

SOD1 and amyotrophic lateral sclerosis: mutations and oligomerization Charcot-Marie-Tooth-linked mutant GARS is toxic to peripheral neurons independent of wild-type GARS levels Impairment of mitochondrial calcium handling in a mtSOD1 cell culture model of motoneuron disease Dysregulation of the autophagy-endolysosomal system in amyotrophic lateral sclerosis and related motor neuron diseases Different human copper-zinc superoxide dismutase mutants, SOD1G93A and SOD1H46R, exert distinct harmful effects on gross phenotype in mice Evaluation of occupational exposure to magnetic fields and motor neuron disease mortality in a population-based cohort Mutation of SOD1 in ALS: a gain of a loss of function Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease Structures of the G85R variant of SOD1 in familial amyotrophic lateral sclerosis Subcellular localisation, secretion, and post-translational processing of normal cochlin, and of mutants causing the sensorineural deafness and vestibular disorder, DFNA9 Misfolded CuZnSOD and amyotrophic lateral sclerosis ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes Ubiquitin-Synaptobrevin Fusion Protein Causes Degeneration of Presynaptic Motor Terminals in Mice Adeno Associated Viral Vector Delivered RNAi for Gene Therapy of SOD1 Amyotrophic Lateral Sclerosis There has been an awakening: Emerging mechanisms of C9orf72 mutations in FTD/ALS Is Modulation of Oxidative Stress an Answer? The State of the Art of Redox Therapeutic Actions in Neurodegenerative Diseases Impaired Autophagy and Defective Mitochondrial Function: Converging Paths on the Road to Motor Neuron Degeneration Dysregulation of glutathione homeostasis in neurodegenerative diseases Risk factors for amyotrophic lateral sclerosis Induced pluripotent stem cells from ALS patients for disease modeling A Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanism Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking Neuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?Spreading of pathology in neurodegenerative diseases: a focus on human studies Prion-like Mechanism in Amyotrophic Lateral Sclerosis: are Protein Aggregates the Key?Molecular chaperone mediated late-stage neuroprotection in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis Hohenheim consensus workshop: copper Alsin, the product of ALS2 gene, suppresses SOD1 mutant neurotoxicity through RhoGEF domain by interacting with SOD1 mutants The complex molecular biology of amyotrophic lateral sclerosis (ALS)The rate and equilibrium constants for a multistep reaction sequence for the aggregation of superoxide dismutase in amyotrophic lateral sclerosis Mechanisms of neurodegeneration in amyotrophic lateral sclerosis TDP-43 identified from a genome wide RNAi screen for SOD1 regulators Late onset of motor neurons in mice overexpressing wild-type peripherin Altered aggregation properties of mutant gamma-crystallins cause inherited cataract Hindlimb motor neurons require Cu/Zn superoxide dismutase for maintenance of neuromuscular junctions Screening of Drugs Inhibiting In vitro Oligomerization of Cu/Zn-Superoxide Dismutase with a Mutation Causing Amyotrophic Lateral Sclerosis Solid-state NMR studies of metal-free SOD1 fibrillar structures.Intermolecular transmission of superoxide dismutase 1 misfolding in living cells.Accelerated s-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper,zinc-superoxide dismutase.Enhanced tethered-flight duration and locomotor activity by overexpression of the human gene SOD1 in Drosophila motorneurons

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P2860

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

http://www.wikidata.org/entity/Q22299419

description

1998 nî lūn-bûn

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1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

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1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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1998年の論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年論文

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1998年论文

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amyotrophic lateral sclerosis