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Spreading of pathology in neurodegenerative diseases: a focus on human studies

Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Calcium-Sensing Receptors of Human Neural Cells Play Crucial Roles in Alzheimer's Disease Molecular Pathological Classification of Neurodegenerative Diseases: Turning towards Precision Medicine Turning On Lights to Stop Neurodegeneration: The Potential of Near Infrared Light Therapy in Alzheimer's and Parkinson's Disease Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer's Disease Pathogenesis The role of macropinocytosis in the propagation of protein aggregation associated with neurodegenerative diseases Transcriptional mutagenesis by 8-oxodG in α-synuclein aggregation and the pathogenesis of Parkinson's disease Potential Therapies by Stem Cell-Derived Exosomes in CNS Diseases: Focusing on the Neurogenic Niche More than a Rumor Spreads in Parkinson's Disease Tau physiology and pathomechanisms in frontotemporal lobar degeneration Conformational analysis of misfolded protein aggregation by FRET and live-cell imaging techniques A Novel Feature Extraction Method with Feature Selection to Identify Golgi-Resident Protein Types from Imbalanced Data Long-Term Effects of Sports Concussions: Bridging the Neurocognitive Repercussions of the Injury with the Newest Neuroimaging Data.Glial contributions to neurodegeneration in tauopathies.The Malignant Protein Puzzle.Cortical brain volume abnormalities associated with few or multiple neuropsychiatric symptoms in Alzheimer's disease Extracellular vesicles as trans-genomic agents: Emerging roles in disease and evolution.Formation and spreading of TDP-43 aggregates in cultured neuronal and glial cells demonstrated by time-lapse imaging.PART, a distinct tauopathy, different from classical sporadic Alzheimer disease.Lysosomal Enzyme Glucocerebrosidase Protects against Aβ1-42 Oligomer-Induced Neurotoxicity.Progression of Seed-Induced Aβ Deposition within the Limbic Connectome Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC's afferent and efferent connections Integrated multimodal imaging in neurodegenerative disease.Extracellular Vesicles from Ovarian Carcinoma Cells Display Specific Glycosignatures.α-synuclein assemblies sequester neuronal α3-Na+/K+-ATPase and impair Na+ gradient O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration.Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease.Haploinsufficiency of cathepsin D leads to lysosomal dysfunction and promotes cell-to-cell transmission of α-synuclein aggregates Molecular Imaging of Neuroinflammation in Neurodegenerative Dementias: The Role of In Vivo PET Imaging Bent out of shape: α-Synuclein misfolding and the convergence of pathogenic pathways in Parkinson's disease.An indicator cell assay for blood-based diagnostics.Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau.A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions A mathematical model of the dynamics of prion aggregates with chaperone-mediated fragmentation Structural and functional properties of prefibrillar α-synuclein oligomers Dura mater is a potential source of Aβ seeds.An Efficient Procedure for Removal and Inactivation of Alpha-Synuclein Assemblies from Laboratory Materials.Decoding Parkinson's Disease Pathogenesis: The Role of Deregulated mRNA Translation.Exposure to bacterial endotoxin generates a distinct strain of α-synuclein fibril.Small heat shock proteins mediate cell-autonomous and -nonautonomous protection in a Drosophila model for environmental-stress-induced degeneration.

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

http://www.wikidata.org/entity/Q28082279

description

2015 nî lūn-bûn

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2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2015 թվականի փետրվարին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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Nature Reviews Neuroscience

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Spreading of pathology in neurodegenerative diseases: a focus on human studies

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P2093

Johannes Brettschneider

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John Q. Trojanowski

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Kelly Del Tredici

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Virginia M.-Y. Lee

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P2860

The spectrum of disease in chronic traumatic encephalopathy

Use of Florbetapir-PET for Imaging β-Amyloid Pathology

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

Transfer of host-derived α synuclein to grafted dopaminergic neurons in rat

Prion-like propagation of mutant superoxide dismutase-1 misfolding in neuronal cells

Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions

α-Synuclein propagates from mouse brain to grafted dopaminergic neurons and seeds aggregation in cultured human cells.

Transmission and spreading of tauopathy in transgenic mouse brain

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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109-20

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2071557

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10.1038/NRN3887

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2

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16

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2015-02-01T00:00:00Z

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1009918670

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25588378

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neurodegeneration

pathogen spread

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4312418

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