ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex
about
SMRTe, a silencing mediator for retinoid and thyroid hormone receptors-extended isoform that is more related to the nuclear receptor corepressorFunctional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemiasThe adenovirus E1A binding protein BS69 is a corepressor of transcription through recruitment of N-CoRAtrophin-1, the dentato-rubral and pallido-luysian atrophy gene product, interacts with ETO/MTG8 in the nuclear matrix and represses transcriptionEvi-1 transforming and repressor activities are mediated by CtBP co-repressor proteinsActivation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion proteinJMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiationAML1-ETO interacts with Sp1 and antagonizes Sp1 transactivity through RUNT domainMyeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1Transcriptional repression by the insulator protein CTCF involves histone deacetylasesThe ETO protein disrupted in t(8;21)-associated acute myeloid leukemia is a corepressor for the promyelocytic leukemia zinc finger proteinmSin3A regulates murine erythroleukemia cell differentiation through association with the TAL1 (or SCL) transcription factorCloning and characterization of a novel human histone deacetylase, HDAC8Repression by Ikaros and Aiolos is mediated through histone deacetylase complexesNet, a negative Ras-switchable TCF, contains a second inhibition domain, the CID, that mediates repression through interactions with CtBP and de-acetylation.Nuclear receptor corepressorsETO2 coordinates cellular proliferation and differentiation during erythropoiesisETO, a target of t(8;21) in acute leukemia, makes distinct contacts with multiple histone deacetylases and binds mSin3A through its oligomerization domainOligomerization of ETO is obligatory for corepressor interactionThe inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathwayProtein-protein interaction panel using mouse full-length cDNAsIdentification of AML1-ETO modulators by chemical genomicsHistone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemiaThe oncogenic fusion protein RUNX1-CBFA2T1 supports proliferation and inhibits senescence in t(8;21)-positive leukaemic cellsAberrant CBFA2T3B gene promoter methylation in breast tumorsAction mechanisms of histone deacetylase inhibitors in the treatment of hematological malignanciesInterplay between Transcription Factors and the Epigenome: Insight from the Role of RUNX1 in LeukemiaMolecular mechanisms of ETS transcription factor-mediated tumorigenesisTranscriptional network control of normal and leukaemic haematopoiesisLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationStructural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activityA TAF4-homology domain from the corepressor ETO is a docking platform for positive and negative regulators of transcriptionStructure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity.Structure of the AML1-ETO NHR3-PKA(RIIα) complex and its contribution to AML1-ETO activityA stable transcription factor complex nucleated by oligomeric AML1–ETO controls leukaemogenesisSilencing mediator for retinoid and thyroid hormone receptors interacts with octamer transcription factor-1 and acts as a transcriptional repressorHistone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells
P2860
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P2860
ETO, fusion partner in t(8;21) acute myeloid leukemia, represses transcription by interaction with the human N-CoR/mSin3/HDAC1 complex
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@ast
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@en
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@nl
type
label
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@ast
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@en
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@nl
prefLabel
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@ast
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@en
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@nl
P2093
P2860
P3181
P356
P1476
ETO, fusion partner in t(8;21) ...... uman N-CoR/mSin3/HDAC1 complex
@en
P2093
P2860
P304
P3181
P356
10.1073/PNAS.95.18.10860
P407
P577
1998-09-01T00:00:00Z