about
P688
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteinsIdentification of VCP/p97, carboxyl terminus of Hsp70-interacting protein (CHIP), and amphiphysin II interaction partners using membrane-based human proteome arraysDPM1, the catalytic subunit of dolichol-phosphate mannose synthase, is tethered to and stabilized on the endoplasmic reticulum membrane by DPM3CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradationChaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complexCHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradationTwo different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topologyCHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activityUbiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligaseCYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligasesUbiquitin ligase ARF-BP1/Mule modulates base excision repairEndoplasmic reticulum protein quality control is determined by cooperative interactions between Hsp/c70 protein and the CHIP E3 ligaseBAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.Akt and CHIP coregulate tau degradation through coordinated interactionsHistone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradationHsp70 and Hsp90 oppositely regulate TGF-β signaling through CHIP/Stub1Brain distribution of carboxy terminus of Hsc70-interacting protein (CHIP) and its nuclear translocation in cultured cortical neurons following heat stress or oxygen-glucose deprivation.Dimerization of the human E3 ligase CHIP via a coiled-coil domain is essential for its activity.PELI1 Selectively Targets Kinase-Active RIP3 for Ubiquitylation-Dependent Proteasomal Degradation.
P921
Q50258453-9D6B3FDE-2FC0-4240-86D1-071AB5ABD398Q50272229-582A779D-31A3-43C6-ADB6-472ADAD7A234Q50274117-AF951F91-A252-46BB-AC3E-ED96CD6C2E89Q50290654-8E69493D-14B5-497A-BE11-D0CCDECDC808Q50290655-E1E46ECD-9735-4E0E-89E9-89FCACDDB775Q50298018-9B6FE7BB-68B5-4C31-A998-09219CAF0591Q50298185-D2006DBC-3F30-4141-BE55-94F4E5823AB7Q50298186-3643309F-1CCE-4473-A99A-CE61C4808CC7
P527
Q22010047-F71C57C6-1F27-43BD-9308-A791DC8C453DQ24290709-2488FEF1-2032-443D-8337-C06D551CC973Q24294183-136FEA59-4AB1-449D-9D03-14224358B7EFQ24294448-34233048-D316-4092-BDFA-E32225B0ED21Q24296740-4591F9D0-76CC-431F-A400-2FC3ED960558Q24296990-40494568-2D94-4003-8D13-343A982F3CC7Q24298589-C50567DF-5E29-47BA-80FD-57348BE152C8Q24301551-6A9EDD6F-6C48-45F2-B907-A273F8CE9B10Q24302505-5BF0FD48-F4C3-4B61-8666-5D6E7AC0B5F7Q24306256-CFC98164-906A-4BC7-8672-C3B467D68B68Q24310116-24116304-76B1-451B-A0BA-6F86015277A9Q24310413-AFC31BF3-DA95-4C2C-BE1F-648D6B22CB80Q24320293-FA00F2B7-4C29-4806-8804-F48C6B7D60BAQ24534836-1BCAC238-D7D7-44C7-A6D9-321D82B356C2Q24656202-4A568429-BA51-45DA-927F-37FB71887961Q24671304-6EBE02BA-73A0-4874-BAF2-B13340B929C1Q28115152-CCE9FC05-26A5-47DB-BD2F-40D4A293287CQ34427541-E9929088-03F5-4F3C-9897-E67210BEE598Q47070627-634D5E3D-7103-497E-9502-1B2B4BA74EECQ54976686-52FC54EE-A4CA-4085-97DE-7B5B52BEC011
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in STIP1 homology and U-box containing protein 1
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
STIP1 homology and U-box containing protein 1
@en
STIP1 homology and U-box containing protein 1
@nl
type
label
STIP1 homology and U-box containing protein 1
@en
STIP1 homology and U-box containing protein 1
@nl
altLabel
CLL-associated antigen KW-8
@en
E3 ubiquitin-protein ligase CHIP
@en
RING-type E3 ubiquitin transferase CHIP
@en
STIP1 homology and U box-containing protein 1
@en
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
@en
STUB1
@en
antigen NY-CO-7
@en
carboxy terminus of Hsp70-interacting protein
@en
heat shock protein A binding protein 2 (c-terminal)
@en
serologically defined colon cancer antigen 7
@en
prefLabel
STIP1 homology and U-box containing protein 1
@en
STIP1 homology and U-box containing protein 1
@nl
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