HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2
about
Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner HippiHIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chainReplacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell deathHuntingtin-interacting protein 1-mediated neuronal cell death occurs through intrinsic apoptotic pathways and mitochondrial alterationsHIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domainsHuntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptorsHuntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivoCalcyon, a novel partner of clathrin light chain, stimulates clathrin-mediated endocytosisScyl1, mutated in a recessive form of spinocerebellar neurodegeneration, regulates COPI-mediated retrograde trafficClathrin-dependent endocytosisIdentification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motifCystamine and cysteamine increase brain levels of BDNF in Huntington disease via HSJ1b and transglutaminase.RNAi-mediated Hip1R silencing results in stable association between the endocytic machinery and the actin assembly machinery.Cloning, expression, purification, crystallization and preliminary crystallographic analysis of pseudo death-effector domain of HIPPI, a molecular partner of Huntingtin-interacting protein HIP-1Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomicsDifferential requirements for AP-2 in clathrin-mediated endocytosisIron dysregulation in Huntington's diseaseCrystal Structure at 2.8 Å of the DLLRKN-containing Coiled-coil Domain of Huntingtin-interacting Protein 1 (HIP1) Reveals a Surface Suitable for Clathrin Light Chain BindingThe Sla2p talin domain plays a role in endocytosis in Saccharomyces cerevisiae.Scd5p and clathrin function are important for cortical actin organization, endocytosis, and localization of sla2p in yeast.Clathrin is important for normal actin dynamics and progression of Sla2p-containing patches during endocytosis in yeastThe phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis.Structural definition of the F-actin-binding THATCH domain from HIP1RA role for epsin N-terminal homology/AP180 N-terminal homology (ENTH/ANTH) domains in tubulin bindingThe ENTH domainMixed lineage kinase 2 interacts with clathrin and influences clathrin-coated vesicle traffickingHuntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survivalHuntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal traffickingHuntingtin interacting protein 1 (HIP1) regulates clathrin assembly through direct binding to the regulatory region of the clathrin light chainDisruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor traffickingAlterations in cortical excitation and inhibition in genetic mouse models of Huntington's disease.Mutant huntingtin impairs Ku70-mediated DNA repair.Huntingtin protein is essential for mitochondrial metabolism, bioenergetics and structure in murine embryonic stem cellsKu70 alleviates neurodegeneration in Drosophila models of Huntington's diseaseEpsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits.Recurrent distal 7q11.23 deletion including HIP1 and YWHAG identified in patients with intellectual disabilities, epilepsy, and neurobehavioral problems.Therapeutic approaches to preventing cell death in Huntington diseaseDoes clathrin pull the fission trigger?Use of a cryptic splice site for the expression of huntingtin interacting protein 1 in select normal and neoplastic tissues.Huntingtin-interacting protein 1: a Merkel cell carcinoma marker that interacts with c-Kit.
P2860
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P2860
HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2
description
2001 nî lūn-bûn
@nan
2001 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@ast
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@en
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@en-gb
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@nl
type
label
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@ast
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@en
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@en-gb
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@nl
prefLabel
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@ast
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@en
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@en-gb
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@nl
P2093
P356
P1476
HIP1 functions in clathrin-med ...... clathrin and adaptor protein 2
@en
P2093
M R Hayden
P S McPherson
V Legendre-Guillemin
P304
P356
10.1074/JBC.C100401200
P407
P577
2001-10-19T00:00:00Z