Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3
about
Regulation of TGF-β signal transduction by mono- and deubiquitylation of SmadsRegulation of TGF-β Superfamily Signaling by SMAD Mono-UbiquitinationCullin-RING ubiquitin ligases in salicylic acid-mediated plant immune signalingThe TGF-β Signaling Regulator PMEPA1 Suppresses Prostate Cancer Metastases to BoneUSP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination.Selective small molecule compounds increase BMP-2 responsiveness by inhibiting Smurf1-mediated Smad1/5 degradationRequirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.The regulation of TGF-β/SMAD signaling by protein deubiquitination.Strategies for assessing proton linkage to bimolecular interactions by global analysis of isothermal titration calorimetry dataDifferential regulation of Smad3 and of the type II transforming growth factor-β receptor in mitosis: implications for signalingNaringenin decreases invasiveness and metastasis by inhibiting TGF-β-induced epithelial to mesenchymal transition in pancreatic cancer cells.Regulation of myofibroblast differentiation by miR-424 during epithelial-to-mesenchymal transition.TRAF4-SMURF2-mediated DAZAP2 degradation is critical for IL-25 signaling and allergic airway inflammation.SEDPHAT--a platform for global ITC analysis and global multi-method analysis of molecular interactions.A tumor suppressor function of Smurf2 associated with controlling chromatin landscape and genome stability through RNF20.Non-degradative ubiquitination in Smad-dependent TGF-β signalingSkeletal Characterization of Smurf2-Deficient Mice and In Vitro Analysis of Smurf2-Deficient ChondrocytesSmad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.Effect of SMURF2 targeting on susceptibility to MEK inhibitors in melanoma.Protein monoubiquitylation: targets and diverse functionsThe Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.Smurf2 regulates the senescence response and suppresses tumorigenesis in mice.The ubiquitin ligase Smurf2 suppresses TGFβ-induced epithelial-mesenchymal transition in a sumoylation-regulated manner.TGF-β signalling and reactive oxygen species drive fibrosis and matrix remodelling in myxomatous mitral valves.SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblastsKRAS protein stability is regulated through SMURF2: UBCH5 complex-mediated β-TrCP1 degradation.Post-translational regulation of TGF-β receptor and Smad signaling.Regulation of the transforming growth factor β pathway by reversible ubiquitylation.The physical basis of renal fibrosis: effects of altered hydrodynamic forces on kidney homeostasis.Crosstalk between kinases and Nedd4 family ubiquitin ligases.Ubiquitin in regulation of spindle apparatus and its positioning: implications in development and disease.Direct Regulation of Alternative Splicing by SMAD3 through PCBP1 Is Essential to the Tumor-Promoting Role of TGF-βJunD Is Required for Proliferation of Prostate Cancer Cells and Plays a Role in Transforming Growth Factor-β (TGF-β)-induced Inhibition of Cell Proliferation.TGF-β Signaling from Receptors to Smads.Ubiquitin signals proteolysis-independent stripping of transcription factors.An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network.Regulation of early xenopus embryogenesis by Smad ubiquitination regulatory factor 2.Downregulation of SMAD2/3:SMAD4 transcriptional activityDownregulation of TGF-beta receptor signalingDiscovery and pharmacological characterization of a new class of prolyl-tRNA synthetase inhibitor for anti-fibrosis therapy.
P2860
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P2860
Ablation of Smurf2 reveals an inhibition in TGF-β signalling through multiple mono-ubiquitination of Smad3
description
2011 nî lūn-bûn
@nan
2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@ast
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@en
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@en-gb
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
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type
label
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@ast
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@en
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@en-gb
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@nl
prefLabel
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@ast
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@en
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@en-gb
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@nl
P2093
P2860
P921
P356
P1433
P1476
Ablation of Smurf2 reveals an ...... e mono-ubiquitination of Smad3
@en
P2093
Chu-Xia Deng
Cuiling Li
Liu-Ya Tang
Motozo Yamashita
Nathan P Coussens
Steven Y Cheng
Xiangchun Wang
Ying E Zhang
P2860
P304
P356
10.1038/EMBOJ.2011.393
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P577
2011-11-30T00:00:00Z