The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment
about
Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle AssemblyReconstituting the kinetochore–microtubule interface: what, why, and howMolecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP and AstrinAn epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis.Lateral to end-on conversion of chromosome-microtubule attachment requires kinesins CENP-E and MCAKNuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic SpindleDynein light chain 1 and a spindle-associated adaptor promote dynein asymmetry and spindle orientation.Dynein light intermediate chains maintain spindle bipolarity by functioning in centriole cohesion.A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.Ubiquitin Receptor Protein UBASH3B Drives Aurora B Recruitment to Mitotic Microtubules.SPAG5 upregulation predicts poor prognosis in cervical cancer patients and alters sensitivity to taxol treatment via the mTOR signaling pathway.Uncovering the molecular machinery of the human spindle--an integration of wet and dry systems biology.Recurrent point mutations in the kinetochore gene KNSTRN in cutaneous squamous cell carcinoma.Small kinetochore associated protein (SKAP) promotes UV-induced cell apoptosis through negatively regulating pre-mRNA processing factor 19 (Prp19).Sensors at centrosomes reveal determinants of local separase activity.High-speed microscopy with an electrically tunable lens to image the dynamics of in vivo molecular complexes.CENP-E kinesin interacts with SKAP protein to orchestrate accurate chromosome segregation in mitosisCdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation.Signaling Scaffold Protein IQGAP1 Interacts with Microtubule Plus-end Tracking Protein SKAP and Links Dynamic Microtubule Plus-end to Steer Cell Migration.The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.Mitotic regulator SKAP forms a link between kinetochore core complex KMN and dynamic spindle microtubules.The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.SKAP, an outer kinetochore protein, is required for mouse germ cell development.Making an effective switch at the kinetochore by phosphorylation and dephosphorylation.Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes.Mechanisms of Chromosome Congression during Mitosis.Kinetochores and disease: keeping microtubule dynamics in check!Regulatory mechanisms of kinetochore-microtubule interaction in mitosis.Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint.Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.Cytoskeletal social networking in the growth cone: How +TIPs mediate microtubule-actin cross-linking to drive axon outgrowth and guidance.Characterization of SKAP/kinastrin isoforms: the N-terminus defines tissue specificity and Pontin binding.Comparative phosphoproteomic analysis of checkpoint recovery identifies new regulators of the DNA damage response.Phosphorylation of Astrin Regulates Its Kinetochore Function.Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells.Tipping the spindle into the right position.Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80.PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencingA proteomic study of mitotic phase-specific interactors of EB1 reveals a role for SXIP-mediated protein interactions in anaphase onset.Sgo1 as a "guardian spirit" for preventing colon tumorigenesis.
P2860
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P2860
The astrin-kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment
description
2011 nî lūn-bûn
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2011 թուականի Մարտին հրատարակուած գիտական յօդուած
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2011 թվականի մարտին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@ast
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@en
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@en-gb
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@nl
type
label
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@ast
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@en
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@en-gb
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@nl
prefLabel
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@ast
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@en
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@en-gb
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@nl
P2860
P921
P3181
P356
P1476
The astrin-kinastrin/SKAP comp ...... cilitates chromosome alignment
@en
P2093
Anja K Dunsch
Emily Linnane
P2860
P304
P3181
P356
10.1083/JCB.201008023
P407
P577
2011-03-14T00:00:00Z