A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation
about
Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactionsA novel role of Sprouty 2 in regulating cellular apoptosisMicroRNA-21 targets Sprouty2 and promotes cellular outgrowthsFunctional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancersHECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2.Establishment of extracellular signal-regulated kinase 1/2 bistability and sustained activation through Sprouty 2 and its relevance for epithelial function.Sprouty2 and Spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoidsThe developing story of Sprouty and cancer.Functional interaction between Env oncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2.G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.Sprouty4 is an endogenous negative modulator of TrkA signaling and neuronal differentiation induced by NGFErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cellsSpry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signalingTesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling.Correlation between microRNA‑21 and sprouty homolog 2 gene expression in multiple myelomaRegulation of cellular levels of Sprouty2 protein by prolyl hydroxylase domain and von Hippel-Lindau proteinsIntersectin 1 enhances Cbl ubiquitylation of epidermal growth factor receptor through regulation of Sprouty2-Cbl interactionSpry1 as a novel regulator of erythropoiesis, EPO/EPOR target, and suppressor of JAK2.An FGFR1-SPRY2 Signaling Axis Limits Basal Cell Proliferation in the Steady-State Airway Epithelium.Sprouty2 interacts with protein kinase C delta and disrupts phosphorylation of protein kinase D1.Intermolecular interactions of Sprouty proteins and their implications in development and disease.Sprouty2 correlates with favorable prognosis of gastric adenocarcinoma via suppressing FGFR2-induced ERK phosphorylation and cancer progression.Downregulation of Sprouty homolog 2 by microRNA-21 inhibits proliferation, metastasis and invasion, however promotes the apoptosis of multiple myeloma cells.The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function.Sprouty-related Ena/vasodilator-stimulated phosphoprotein homology 1-domain-containing protein (SPRED1), a tyrosine-protein phosphatase non-receptor type 11 (SHP2) substrate in the Ras/extracellular signal-regulated kinase (ERK) pathway.Spry regulation of FGF signalingDyrk1A, a serine/threonine kinase, is involved in ERK and Akt activation in the brain of hyperhomocysteinemic mice.Sprouty2 is involved in the control of osteoblast proliferation and differentiation through the FGF and BMP signaling pathways.Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling.SPRY2 binds GRB2Direct binding of PP2A to Sprouty2 and phosphorylation changes are a prerequisite for ERK inhibition downstream of fibroblast growth factor receptor stimulation.Differential Effects of Variations at Codon 106 on Sprouty2 Functions in Lung Cancer-Derived Cells.
P2860
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P2860
A Src homology 3-binding sequence on the C terminus of Sprouty2 is necessary for inhibition of the Ras/ERK pathway downstream of fibroblast growth factor receptor stimulation
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A Src homology 3-binding seque ...... th factor receptor stimulation
@ast
A Src homology 3-binding seque ...... th factor receptor stimulation
@en
A Src homology 3-binding seque ...... th factor receptor stimulation
@en-gb
A Src homology 3-binding seque ...... th factor receptor stimulation
@nl
type
label
A Src homology 3-binding seque ...... th factor receptor stimulation
@ast
A Src homology 3-binding seque ...... th factor receptor stimulation
@en
A Src homology 3-binding seque ...... th factor receptor stimulation
@en-gb
A Src homology 3-binding seque ...... th factor receptor stimulation
@nl
prefLabel
A Src homology 3-binding seque ...... th factor receptor stimulation
@ast
A Src homology 3-binding seque ...... th factor receptor stimulation
@en
A Src homology 3-binding seque ...... th factor receptor stimulation
@en-gb
A Src homology 3-binding seque ...... th factor receptor stimulation
@nl
P2093
P2860
P3181
P356
P1476
A Src homology 3-binding seque ...... th factor receptor stimulation
@en
P2093
Chee Wai Fong
Chye Yun Yu
Dieu-Hung Lao
Graeme R Guy
Hwei Fen Leong
Lai Peng Tai
Permeen Yusoff
Tzuen Yih Saw
P2860
P304
29993-30000
P3181
P356
10.1074/JBC.M604044200
P407
P577
2006-10-06T00:00:00Z