Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
about
PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitryMass Spectrometry-Based Proteomics for Investigating DNA Damage-Associated Protein UbiquitylationFunctions of Ubiquitin and SUMO in DNA Replication and Replication StressQuantifying ubiquitin signalingRPA-coated single-stranded DNA as a platform for post-translational modifications in the DNA damage responseThe emerging roles of GPRC5A in diseasesStructure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repairRegulation of translesion DNA synthesis: Posttranslational modification of lysine residues in key proteinsSystematic E2 screening reveals a UBE2D-RNF138-CtIP axis promoting DNA repairExposure of Human Lung Cells to Tobacco Smoke Condensate Inhibits the Nucleotide Excision Repair PathwayStructural basis of human PCNA sliding on DNA.The Ddc1-Mec3-Rad17 sliding clamp regulates histone-histone chaperone interactions and DNA replication-coupled nucleosome assembly in budding yeastPAF and EZH2 induce Wnt/β-catenin signaling hyperactivation.SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.Epigenome Maintenance in Response to DNA DamageThe DNA damage response: the omics era and its impact.Convergence of ubiquitylation and phosphorylation signaling in rapamycin-treated yeast cells.Uncovering global SUMOylation signaling networks in a site-specific mannerPAF-mediated MAPK signaling hyperactivation via LAMTOR3 induces pancreatic tumorigenesis.p15PAF is an intrinsically disordered protein with nonrandom structural preferences at sites of interaction with other proteins.Middle-down mass spectrometry enables characterization of branched ubiquitin chains.Structurally distinct ubiquitin- and sumo-modified PCNA: implications for their distinct roles in the DNA damage response.Expression of pre-selected TMEMs with predicted ER localization as potential classifiers of ccRCC tumors.System-wide identification of wild-type SUMO-2 conjugation sites.Genetic Interactions Implicating Postreplicative Repair in Okazaki Fragment Processing.Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation.Identification of a Recognizable Progressive Skeletal Dysplasia Caused by RSPRY1 Mutations.Posttranslational Regulation of Human DNA Polymerase ι.Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuronPAF-Wnt signaling-induced cell plasticity is required for maintenance of breast cancer cell stemness.Protein monoubiquitylation: targets and diverse functionsThe ubiquitin ligase Ubr4 controls stability of podocin/MEC-2 supercomplexes.Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing.RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage responseA ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repairDNA damage tolerance: a double-edged sword guarding the genomeMutations in FAM111B cause hereditary fibrosing poikiloderma with tendon contracture, myopathy, and pulmonary fibrosis.Using the ubiquitin-modified proteome to monitor protein homeostasis function.Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response.Proteomics insights into DNA damage response and translating this knowledge to clinical strategies.
P2860
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P2860
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@ast
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@en
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@en-gb
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@nl
type
label
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@ast
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@en
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@en-gb
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@nl
prefLabel
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@ast
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@en
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@en-gb
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Systems-wide analysis of ubiqu ...... itylation in DNA-damage bypass
@en
P2093
Chunaram Choudhary
Jon W Poulsen
Lou K Povlsen
Niels Mailand
Sara L Poulsen
Sebastian A Wagner
P2860
P2888
P304
P3181
P356
10.1038/NCB2579
P407
P577
2012-10-01T00:00:00Z
P5875
P6179
1020971905