Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate
about
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypassA membrane-type-1 matrix metalloproteinase (MT1-MMP)-discoidin domain receptor 1 axis regulates collagen-induced apoptosis in breast cancer cellsStructure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repairA proteomic chronology of gene expression through the cell cycle in human myeloid leukemia cellsStructural basis of human PCNA sliding on DNA.PAF and EZH2 induce Wnt/β-catenin signaling hyperactivation.SIVA1 directs the E3 ubiquitin ligase RAD18 for PCNA monoubiquitination.PAF-mediated MAPK signaling hyperactivation via LAMTOR3 induces pancreatic tumorigenesis.p15PAF is an intrinsically disordered protein with nonrandom structural preferences at sites of interaction with other proteins.Weighted frequent gene co-expression network mining to identify genes involved in genome stability.p15(PAF) is an Rb/E2F-regulated S-phase protein essential for DNA synthesis and cell cycle progressionAPC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage.Targeting RNA binding proteins involved in neurodegeneration.Paf15 expression correlates with rectal cancer prognosis, cell proliferation and radiation response.A Functional Proteomics Perspective of DBC1 as a Regulator of Transcription.Moonlighting and pleiotropy within two regulators of the degradation machinery: the proteasome lid and the CSN.Controlling the response to DNA damage by the APC/C-Cdh1.Regulation of Rad6/Rad18 Activity During DNA Damage Tolerance.Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells.miR-200b induces cell cycle arrest and represses cell growth in esophageal squamous cell carcinoma.Disentangling polydispersity in the PCNA-p15PAF complex, a disordered, transient and multivalent macromolecular assembly.A functional role for NS5ATP9 in the induction of HCV NS5A-mediated autophagy.Expression of KIAA0101 protein is associated with poor survival of esophageal cancer patients and resistance to cisplatin treatment in vitro.The spindle checkpoint, APC/C(Cdc20), and APC/C(Cdh1) play distinct roles in connecting mitosis to S phase.NS5ATP9 contributes to inhibition of cell proliferation by hepatitis C virus (HCV) nonstructural protein 5A (NS5A) via MEK/extracellular signal regulated kinase (ERK) pathway.Elevated KIAA0101 expression is a marker of recurrence in human gastric cancer.Global identification of modular cullin-RING ligase substratesVariant 2 of KIAA0101, antagonizing its oncogenic variant 1, might be a potential therapeutic strategy in hepatocellular carcinoma.NS5ATP9 Promotes Beclin 1-Dependent Starvation-Induced Autophagy of Hepatoblastoma Cells.NS5ATP9 suppresses activation of human hepatic stellate cells, possibly via inhibition of Smad3/phosphorylated-Smad3 expression.Erratum to: Controlling the response to DNA damage by the APC/C-Cdh1.Unbiased transcriptome signature of in vivo cell proliferation reveals pro- and antiproliferative gene networksVariant 1 of KIAA0101, overexpressed in hepatocellular carcinoma, prevents doxorubicin-induced apoptosis by inhibiting p53 activation.PAF makes it EZ(H2) for β-catenin transactivation.The dark side of the ring: role of the DNA sliding surface of PCNA.PAF promotes stemness and radioresistance of glioma stem cells.KIAA0101 double monoubiquitinationPAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis.p15PAF binding to PCNA modulates the DNA sliding surfaceLow Oxygen Levels Induce Early Luteinization Associated Changes in Bovine Granulosa Cells
P2860
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P2860
Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@ast
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@en
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@en-gb
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@nl
type
label
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@ast
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@en
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@en-gb
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@nl
prefLabel
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@ast
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@en
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@en-gb
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@nl
P2093
P2860
P3181
P356
P1476
Proliferating cell nuclear ant ...... ng complex/cyclosome substrate
@en
P2093
Alberto Ciccia
Andrew E H Elia
Michael J Emanuele
P2860
P304
P3181
P356
10.1073/PNAS.1106136108
P407
P577
2011-06-14T00:00:00Z