The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability - Test2 - elhamkhani - TriplyDB

The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability

The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability

http://www.wikidata.org/entity/Q24299896

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Substrate preference and phosphatidylinositol monophosphate inhibition of the catalytic domain of the Per-Arnt-Sim domain kinase PASKIN Ubiquitin-specific protease 19 (USP19) regulates hypoxia-inducible factor 1α (HIF-1α) during hypoxia The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity Regulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouse The hypoxia-inducible factor pathway, prolyl hydroxylase domain protein inhibitors, and their roles in bone repair and regeneration Small molecule Plasmodium FKBP35 inhibitor as a potential antimalaria agent Crystal structure of Plasmodium vivax FK506-binding protein 25 reveals conformational changes responsible for its noncanonical activity Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approaches Oxygen sensing in Drosophila: multiple isoforms of the prolyl hydroxylase fatiga have different capacity to regulate HIFalpha/Sima The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube The role of PHD2 mutations in the pathogenesis of erythrocytosis.The FKBP38 catalytic domain binds to Bcl-2 via a charge-sensitive loop.A novel calmodulin-Ca2+ target recognition activates the Bcl-2 regulator FKBP38.Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate.Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells.Rheb GTPase controls apoptosis by regulating interaction of FKBP38 with Bcl-2 and Bcl-XL Toxoplasma gondii activates hypoxia-inducible factor (HIF) by stabilizing the HIF-1alpha subunit via type I activin-like receptor kinase receptor signaling.Human high-altitude adaptation: forward genetics meets the HIF pathway.Involvement of BH4 domain of bcl-2 in the regulation of HIF-1-mediated VEGF expression in hypoxic tumor cells.FKBP38 peptidylprolyl isomerase promotes the folding of cystic fibrosis transmembrane conductance regulator in the endoplasmic reticulum Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90 CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells.Prolyl hydroxylase domain protein 2 (PHD2) binds a Pro-Xaa-Leu-Glu motif, linking it to the heat shock protein 90 pathway Melanoma antigen-11 inhibits the hypoxia-inducible factor prolyl hydroxylase 2 and activates hypoxic response.The Zinc Finger of Prolyl Hydroxylase Domain Protein 2 Is Essential for Efficient Hydroxylation of Hypoxia-Inducible Factor α.The role of HIF prolyl hydroxylases in tumour growth.Hypoxia-inducible factor-mediated induction of WISP-2 contributes to attenuated progression of breast cancer.Induction of long noncoding RNA MALAT1 in hypoxic mice Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets.Hypoxia-inducible factors--regulation, role and comparative aspects in tumourigenesis.An overview of cyclophilins in human cancers.HIF-prolyl hydroxylases and cardiovascular diseases.Prolyl 4-hydroxylases, master regulators of the hypoxia response.Therapeutic inhibition of prolyl hydroxylase domain-containing enzymes in surgery: putative applications and challenges.Role of reactive oxygen species in the regulation of HIF-1 by prolyl hydroxylase 2 under mild hypoxia.Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.FKBP38 protects Bcl-2 from caspase-dependent degradation.

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The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability

http://www.wikidata.org/entity/Q24299896

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

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Molecular and Cellular Biology

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The peptidyl prolyl cis/trans ...... oxylase PHD2 protein stability

@en

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Dörthe M Katschinski

http://www.w3.org/2001/XMLSchema#string

Frank Edlich

http://www.w3.org/2001/XMLSchema#string

Gieri Camenisch

http://www.w3.org/2001/XMLSchema#string

Katarzyna J Nytko

http://www.w3.org/2001/XMLSchema#string

Philippe A Hasgall

http://www.w3.org/2001/XMLSchema#string

Renato Wirthner

http://www.w3.org/2001/XMLSchema#string

Roland H Wenger

http://www.w3.org/2001/XMLSchema#string

Sandra Barth

http://www.w3.org/2001/XMLSchema#string

P2860

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

A conserved family of prolyl-4-hydroxylases that modify HIF

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

The candidate tumor suppressor ING4 represses activation of the hypoxia inducible factor (HIF).

Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin.

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor.

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3758-68

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scholarly article

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10.1128/MCB.01324-06

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10

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27

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Daniel P Stiehl

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2007-05-01T00:00:00Z

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17353276

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