Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element - Test2 - elhamkhani - TriplyDB

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

http://www.wikidata.org/entity/Q24528175

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The peptidyl prolyl cis/trans isomerase FKBP38 determines hypoxia-inducible transcription factor prolyl-4-hydroxylase PHD2 protein stability IOP1, a novel hydrogenase-like protein that modulates hypoxia-inducible factor-1alpha activity Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α)Regulation of hypoxia-inducible factor-1alpha by NF-kappaB The hypoxia-inducible factor pathway, prolyl hydroxylase domain protein inhibitors, and their roles in bone repair and regeneration Hypoxia-inducible factors regulate T cell metabolism and function The novel WD-repeat protein Morg1 acts as a molecular scaffold for hypoxia-inducible factor prolyl hydroxylase 3 (PHD3)Increased prolyl 4-hydroxylase domain proteins compensate for decreased oxygen levels. Evidence for an autoregulatory oxygen-sensing system.Molecular mechanisms of HIF-1alpha modulation induced by oxygen tension and BMP2 in glioblastoma derived cells.Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.Differentiation-induced uroplakin III expression promotes urothelial cell death in response to uropathogenic E. coli Src activates HIF-1α not through direct phosphorylation of HIF-1α specific prolyl-4 hydroxylase 2 but through activation of the NADPH oxidase/Rac pathway.Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection.Erythropoietin after a century of research: younger than ever.The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop.The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH.Chenodeoxycholic Acid Reduces Hypoxia Inducible Factor-1α Protein and Its Target Genes.HIF-1α and HIF-2α degradation is differentially regulated in nucleus pulposus cells of the intervertebral disc Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis.Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.Hypoxia-inducible miR-182 enhances HIF1α signaling via targeting PHD2 and FIH1 in prostate cancer.Expression of prolyl hydroxylases (PHDs) is selectively controlled by HIF-1 and HIF-2 proteins in nucleus pulposus cells of the intervertebral disc: distinct roles of PHD2 and PHD3 proteins in controlling HIF-1α activity in hypoxia Identification and functional characterization of pVHL-dependent cell surface proteins in renal cell carcinoma.Hypoxia-inducible factor-1alpha stabilization in nonhypoxic conditions: role of oxidation and intracellular ascorbate depletion.Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancer.Prolyl hydroxylase 3 (PHD3) modulates catabolic effects of tumor necrosis factor-α (TNF-α) on cells of the nucleus pulposus through co-activation of nuclear factor κB (NF-κB)/p65 signaling.Redox signaling pathways involved in neuronal ischemic preconditioning CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells.Redox regulation of the hypoxia-inducible factor.Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress.Regulation of gene expression by hypoxia: integration of the HIF-transduced hypoxic signal at the hypoxia-responsive element Function and expression of prolyl hydroxylase 3 in cancers.Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells The role of HIF prolyl hydroxylases in tumour growth.Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38.Prolyl-hydroxylase 3: Evolving Roles for an Ancient Signaling Protein Prolyl 4-hydroxylases, master regulators of the hypoxia response.

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P2860

Regulation of the prolyl hydroxylase domain protein 2 (phd2/egln-1) gene: identification of a functional hypoxia-responsive element

http://www.wikidata.org/entity/Q24528175

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2005 nî lūn-bûn

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2005年の論文

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Regulation of the prolyl hydro ...... nal hypoxia-responsive element

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Eric Metzen

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Jan H Marxsen

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Kathrin Doege

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Thomas Hellwig-Bürgel

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Wolfgang Jelkmann

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P2860

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

A conserved family of prolyl-4-hydroxylases that modify HIF

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

Comprehensive analysis of CpG islands in human chromosomes 21 and 22

HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

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711-717

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10.1042/BJ20041736

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P433

Pt 3

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387

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Daniel P Stiehl

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2005-05-01T00:00:00Z

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8164653

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15563275

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1135001

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