RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis
about
Retaining MKP1 expression and attenuating JNK-mediated apoptosis by RIP1 for cisplatin resistance through miR-940 inhibitionReceptor interactive protein kinase 3 promotes Cisplatin-triggered necrosis in apoptosis-resistant esophageal squamous cell carcinoma cellsSynergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis.RIP3 is downregulated in human myeloid leukemia cells and modulates apoptosis and caspase-mediated p65/RelA cleavageDifferential roles of RIPK1 and RIPK3 in TNF-induced necroptosis and chemotherapeutic agent-induced cell death.SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells.How to target apoptosis signaling pathways for the treatment of pediatric cancersIntrinsic and chemo-sensitizing activity of SMAC-mimetics on high-risk childhood acute lymphoblastic leukemia.Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers.Receptor-interacting protein 1 increases chemoresistance by maintaining inhibitor of apoptosis protein levels and reducing reactive oxygen species through a microRNA-146a-mediated catalase pathway.The LEF1/CYLD axis and cIAPs regulate RIP1 deubiquitination and trigger apoptosis in selenite-treated colorectal cancer cells.Inhibitor of apoptosis proteins in pediatric leukemia: molecular pathways and novel approaches to therapy.Inhibitor of Apoptosis (IAP) proteins in hematological malignancies: molecular mechanisms and therapeutic opportunities.Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells.Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis.Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation.Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis.Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes.RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex.Highlights of the third International Conference on Immunotherapy in Pediatric Oncology.Cooperative TRAIL production mediates IFNα/Smac mimetic-induced cell death in TNFα-resistant solid cancer cells.RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis.Smac mimetic LCL161 supports neuroblastoma chemotherapy in a drug class-dependent manner and synergistically interacts with ALK inhibitor TAE684 in cells with ALK mutation F1174L.The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells.Impairment of antioxidant defense via glutathione depletion sensitizes acute lymphoblastic leukemia cells for Smac mimetic-induced cell death.Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NFκB, RIP1 and TNF-α.Inhibitors of apoptosis: clinical implications in cancer.
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RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@ast
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@en
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@en-gb
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@nl
type
label
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@ast
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@en
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@en-gb
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@nl
prefLabel
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@ast
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@en
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@en-gb
RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@nl
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RIP1 is required for IAP inhib ...... chemotherapy-induced apoptosis
@en
P2093
H Schoeneberger
J Leibacher
K-M Debatin
M J M Bertrand
N Vanlangenakker
S Cristofanon
P2860
P2888
P304
P3181
P356
10.1038/LEU.2011.353
P407
P577
2012-05-01T00:00:00Z
P5875
P6179
1049850273