CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability
about
The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex componentsMutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia.SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myelomaPIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcriptionPhosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complexMechanisms of Hsp90 regulationReview: The HSP90 molecular chaperone-an enigmatic ATPaseSubstrate recognition and function of the R2TP complex in response to cellular stressTherapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shiftNutrient regulation of the mTOR complex 1 signaling pathwayStructure of Minimal Tetratricopeptide Repeat Domain Protein Tah1 Reveals Mechanism of Its Interaction with Pih1 and Hsp90Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response.The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.The Proteasome Subunit Rpn8 Interacts with the Small Nucleolar RNA Protein (snoRNP) Assembly Protein Pih1 and Mediates Its Ubiquitin-independent Degradation in Saccharomyces cerevisiae.A Novel Interaction of Ecdysoneless (ECD) Protein with R2TP Complex Component RUVBL1 Is Required for the Functional Role of ECD in Cell Cycle ProgressionA genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylationRuvbL1 and RuvbL2 enhance aggresome formation and disaggregate amyloid fibrils.Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2Biophysical characterization and modeling of human Ecdysoneless (ECD) protein supports a scaffolding functionThe Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System.Genetic and physical interactions between Tel2 and the Med15 Mediator subunit in Saccharomyces cerevisiae.Nutrient signaling to mTOR and cell growth.Drosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signalingThe leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma.Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteomemTOR complex 2 signaling and functionsGenetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1.RNA-guided isomerization of uridine to pseudouridine--pseudouridylation.Mechanism of the AAA+ ATPases pontin and reptin in the biogenesis of H/ACA RNPs.Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signalingSmall molecule therapeutics targeting F-box proteins in cancer.Proteomic and Genomic Analyses of the Rvb1 and Rvb2 Interaction Network upon Deletion of R2TP Complex ComponentsA Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex.ATR signalling: more than meeting at the fork.Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1.Overexpression of TELO2 decreases survival in human high-grade gliomas.Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries
P2860
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P2860
CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@ast
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@en
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@en-gb
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@nl
type
label
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@ast
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@en
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@en-gb
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@nl
prefLabel
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@ast
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@en
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@en-gb
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@nl
P2093
P50
P921
P3181
P1433
P1476
CK2 phospho-dependent binding ...... al for mTOR and SMG1 stability
@en
P2093
Carrie A Adelman
Hiroyuki Takai
J Mark Skehel
Sarah Maslen
Simon J Boulton
P304
P3181
P356
10.1016/J.MOLCEL.2010.08.037
P407
P577
2010-09-24T00:00:00Z