Category:Titia_de_LangeTitia_de_LangeTitia_de_LangeTitia_de_LangeTitia_de_LangeTitia_de_Lange%D0%94%D0%B5_%D0%9B%D0%B0%D0%BD%D0%B3%D0%B5,_%D0%A2%D0%B8%D1%82%D0%B8%D1%8F%D0%A2%D1%96%D1%82%D1%96%D1%8F_%D0%B4%D0%B5_%D0%9B%D0%B0%D0%BD%D0%B3%D0%B5Q2436934%E8%92%82%E8%92%82%E4%BA%9A%C2%B7%E5%BE%B7%E6%9C%97%E5%8E%84
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Tankyrase, a poly(ADP-ribose) polymerase at human telomeresMammalian telomeres end in a large duplex loopKu binds telomeric DNA in vitroIdentification of human Rap1: implications for telomere evolutionCell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeresTIN2 is a tankyrase 1 PARP modulator in the TRF1 telomere length control complexA mammalian factor that binds telomeric TTAGGG repeats in vitroTel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexesRap1 affects the length and heterogeneity of human telomeresPOT1-interacting protein PIP1: a telomere length regulator that recruits POT1 to the TIN2/TRF1 complexCK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stabilityERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomesPOT1 as a terminal transducer of TRF1 telomere length controlA human telomeric proteinTel2 regulates the stability of PI3K-related protein kinasesIn vivo stoichiometry of shelterin componentsHuman telomeres contain two distinct Myb-related proteins, TRF1 and TRF2Telomere protection by mammalian Pot1 requires interaction with Tpp1Control of telomere length by the human telomeric protein TRF1Control of human telomere length by TRF1 and TRF2Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpointTelomere protection by TPP1 is mediated by POT1a and POT1bThe telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response53BP1: pro choice in DNA repairNMR structure of the hRap1 Myb motif reveals a canonical three-helix bundle lacking the positive surface charge typical of Myb DNA-binding domainsStructure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins53BP1 regulates DSB repair using Rif1 to control 5' end resectionTRF2 Protects Human Telomeres from End-to-End FusionsHomologous recombination generates T-loop-sized deletions at human telomeresATM and ATR Signaling Regulate the Recruitment of Human Telomerase to TelomeresChromosomal mapping of the tankyrase gene in human and mouseFor better or worse? Telomerase inhibition and cancerCell cycle dependent localization of the telomeric PARP, tankyrase, to nuclear pore complexes and centrosomesDNA binding features of human POT1: a nonamer 5'-TAGGGTTAG-3' minimal binding site, sequence specificity, and internal binding to multimeric sitesShelterin: the protein complex that shapes and safeguards human telomeresTIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeresComparison of the human and mouse genes encoding the telomeric protein, TRF1: chromosomal localization, expression and conserved protein domainsSenescence Induced by Altered Telomere State, Not Telomere LossMutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages
P50
Q22008022-1F4A96BF-7C7B-42FC-B2A1-17AC56A52443Q22009893-958DFC12-259D-486C-841D-3D9A99813E38Q22010395-F8BBF163-70C2-43ED-A378-4A8AEE1DDFC9Q22254239-BD8C2538-543B-49EF-9B32-14ED00F167CDQ22254585-83030ACA-FD68-44E7-AF9E-7F84BDF3A6ABQ24292755-E37A62A1-444B-4768-95F6-DB7C8536D4E4Q24293724-0FC9A8A5-5527-413D-BD16-9C32CD160B7FQ24297874-738E6E3B-781A-4F66-B719-8B42D8B79A5BQ24298023-C36E11F8-3BD5-490C-ADDA-B07D9AF94EC5Q24298357-01742C42-8093-4A81-A02D-4A4EE94E497EQ24300796-902C78FB-227F-43E7-A087-EA22F5FC4B9FQ24302611-ACD3CCA8-B2D7-47A5-B34F-1DE2F150BCC7Q24302841-9B778D74-BA18-4A6B-A155-233F01F77F90Q24304466-E9CC4F41-436D-4B4B-8358-5171B98658EFQ24304948-26E7B6D0-2C1B-461D-B9DF-3BA57946C917Q24312021-166193FC-3096-4B6A-A85D-2DD70C77C2B7Q24317670-2DCB81E9-DF2C-4B93-A3D8-C2751F446791Q24319841-89B4407A-7375-413C-B67D-DB1EF244AABEQ24320111-517BE44B-4B8E-40A4-8E54-EE2AE7D2000CQ24554302-098B86FC-4481-4367-947C-D83E7A60563BQ24562757-F29FF796-EEAD-4473-B95D-41DDE5BFA773Q24654732-04422422-6EA7-46FD-9B20-55C67BB830DCQ24799005-BD404DAF-B8BB-49BF-A942-15FBCBF0D4BEQ26828847-B9383EFF-398F-47C0-893B-25718E0AE33BQ27634722-5C0517F8-3B44-479E-A950-7DD157C775EAQ27634733-6B555BF9-D210-4C78-82BE-8FC66FCA1A16Q27649552-69C9B529-B66C-4CF3-A578-69831353F863Q28000120-4B7487E5-B82D-4A24-B999-E2B52CC96E5BQ28111898-FFA98FE6-8265-4FD5-96D6-2DAE61EB8910Q28116970-6177A27B-8436-47C4-843B-FBC36468683FQ28117859-47D81496-2260-43F1-BF39-E2A3A3DAE53CQ28141219-478BFDBB-AD0C-43C0-B4D8-4DF089254846Q28142778-8CA300F9-5739-48AB-BF27-144D30F3FC5AQ28145946-2037D716-2274-4947-A915-ED5D5410C688Q28238009-599D641F-1F19-4AB0-9A92-A5C14B449717Q28272546-C9999394-5C31-40D2-A421-AB161EB35BFCQ28277505-F16B9552-B8A8-4813-9625-434367629B60Q28301774-33CE916D-1B34-4663-9ABA-D6A133246A78Q28315731-EF58D865-BF7C-4A95-AF6D-69987FD67436Q28506028-92DCBCED-A98E-463E-8850-E9569B9CBD30
P50
description
Dutch geneticist
@en
Dutch geneticist
@en-ca
Dutch geneticist
@en-gb
Nederlands klinische genetica
@nl
biologiste moléculaire et généticienne néerlandaise
@fr
genetista neerlandesa
@es
niederländische Zellbiologin und Genetikerin
@de
عالمة وراثة هولندية
@ar
name
Titia de Lange
@ast
Titia de Lange
@ca
Titia de Lange
@de
Titia de Lange
@en
Titia de Lange
@es
Titia de Lange
@fr
Titia de Lange
@nl
Titia de Lange
@pt
Titia de Lange
@sl
Де Ланге, Тития
@ru
type
label
Titia de Lange
@ast
Titia de Lange
@ca
Titia de Lange
@de
Titia de Lange
@en
Titia de Lange
@es
Titia de Lange
@fr
Titia de Lange
@nl
Titia de Lange
@pt
Titia de Lange
@sl
Де Ланге, Тития
@ru
altLabel
Titia De Lange
@de
Titia Delange
@de
prefLabel
Titia de Lange
@ast
Titia de Lange
@ca
Titia de Lange
@de
Titia de Lange
@en
Titia de Lange
@es
Titia de Lange
@fr
Titia de Lange
@nl
Titia de Lange
@pt
Titia de Lange
@sl
Де Ланге, Тития
@ru
P166
P463
P1006
P214
P244
P268
P269
P1006
P1053
B-8263-2011
P1153
7006070237