Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes
about
Dual roles of the transcription factor grainyhead-like 2 (GRHL2) in breast cancerMutations in GRHL2 result in an autosomal-recessive ectodermal Dysplasia syndromeGrainyhead-like 2 (GRHL2) inhibits keratinocyte differentiation through epigenetic mechanismTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneRole of Telomerase in the Cardiovascular SystemGene expression correlations in human cancer cell lines define molecular interaction networks for epithelial phenotypeThe transcription factors Grainyhead-like 2 and NK2-homeobox 1 form a regulatory loop that coordinates lung epithelial cell morphogenesis and differentiationExpression of transcription factor grainyhead-like 2 is diminished in cervical cancer.Bisphosphonates induce senescence in normal human oral keratinocytes.The p63 Gene Is Regulated by Grainyhead-like 2 (GRHL2) through Reciprocal Feedback and Determines the Epithelial Phenotype in Human KeratinocytesGRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification.Marked overlap of four genetic syndromes with dyskeratosis congenita confounds clinical diagnosisGrhl2 reduces invasion and migration through inhibition of TGFβ-induced EMT in gastric cancer.Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis.Causes and consequences of epigenetic regulation in wound healing.Diverse expression patterns of the EMT suppressor grainyhead-like 2 (GRHL2) in normal and tumour tissues.Grainyhead-like 2 regulates epithelial plasticity and stemness in oral cancer cells.Expression and role of grainyhead-like 2 in gastric cancer.Differential downregulation of telomerase activity by bortezomib in multiple myeloma cells-multiple regulatory pathways in vitro and ex vivo.Grainyhead-like 2 in development and cancer.Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2.Epithelial-mesenchymal transition, a spectrum of states: Role in lung development, homeostasis, and disease.Roles of Grainyhead-like transcription factors in cancer.Identification of a novel progenitor cell marker, grainyhead-like 2 in the developing pituitary.miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila.Grainyhead-like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety-like behaviors in aged mice.hTERT peptide fragment GV1001 demonstrates radioprotective and antifibrotic effects through suppression of TGF‑β signaling.Grainyhead-like 2 (GRHL2) knockout abolishes oral cancer development through reciprocal regulation of the MAP kinase and TGF-β signaling pathways.
P2860
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P2860
Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes
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2010 nî lūn-bûn
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2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
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2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված
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2010年の論文
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2010年学术文章
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Grainyhead-like 2 enhances the ...... in normal human keratinocytes
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Grainyhead-like 2 enhances the ...... in normal human keratinocytes
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Grainyhead-like 2 enhances the ...... in normal human keratinocytes
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P2093
P2860
P921
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Grainyhead-like 2 enhances the ...... in normal human keratinocytes
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Ki-Hyuk Shin
No-Hee Park
Qinghua Dong
Reuben H Kim
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P304
P3181
P356
10.1074/JBC.M110.103812
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P577
2010-12-24T00:00:00Z