Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity - Test2 - elhamkhani - TriplyDB

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

http://www.wikidata.org/entity/Q29615388

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Normal human chromosomes have long G-rich telomeric overhangs at one end Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeres Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2 Structural basis of selective ubiquitination of TRF1 by SCFFbx4 Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase A WD-repeat protein stabilizes ORC binding to chromatin Grainyhead-like 2 enhances the human telomerase reverse transcriptase gene expression by inhibiting DNA methylation at the 5'-CpG island in normal human keratinocytes The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity Telomerase inhibitor PinX1 provides a link between TRF1 and telomerase to prevent telomere elongation TRF1 is a dimer and bends telomeric DNA POT1 association with TRF2 regulates telomere length Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro POT1 and TRF2 cooperate to maintain telomeric integrity Biography of Carol W. Greider Deletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndrome Human telomerase and its regulation Allosteric inhibitors of telomerase: oligonucleotide N3'-->P5' phosphoramidates Identification of two RNA-binding proteins associated with human telomerase RNA Control of human telomere length by TRF1 and TRF2 Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation Telomere elongation in immortal human cells without detectable telomerase activity Telomere shortening and apoptosis in telomerase-inhibited human tumor cells Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1 Functional subdomain in the ankyrin domain of tankyrase 1 required for poly(ADP-ribosyl)ation of TRF1 and telomere elongation Ciliate telomerase RNA structural features Telomere dysfunction and chromosome instability Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging Isolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissues NFX1 interacts with mSin3A/histone deacetylase to repress hTERT transcription in keratinocytes Cytotoxic T cell immunity against telomerase reverse transcriptase in humans Telomeres shorten more slowly in long-lived birds and mammals than in short-lived ones Involvement of 14-3-3 proteins in nuclear localization of telomerase Is telomerase reactivation associated with the down-regulation of TGF beta receptor-II expression in human breast cancer?Complex roles for telomeres and telomerase in breast carcinogenesis Long-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: an in vitro study Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function.Strict control of telomerase activation using Cre-mediated inversion.Telomerase: The Devil Inside Structure and function of the telomeric CST complex Telomeres and telomerase as therapeutic targets to prevent and treat age-related diseases

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Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity

http://www.wikidata.org/entity/Q29615388

description

1992 nî lūn-bûn

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1992 թուականի Մայիսին հրատարակուած գիտական յօդուած

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1992 թվականի մայիսին հրատարակված գիտական հոդված

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1992年の論文

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1992年論文

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1992年論文

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1992年論文

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1992年論文

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1992年論文

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1992年论文

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Telomere shortening associated ...... ch express telomerase activity

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Telomere shortening associated ...... ch express telomerase activity

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Telomere shortening associated ...... ch express telomerase activity

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Telomere shortening associated ...... ch express telomerase activity

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Telomere shortening associated ...... ch express telomerase activity

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Telomere shortening associated ...... ch express telomerase activity

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The EMBO Journal

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Telomere shortening associated ...... ch express telomerase activity

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Avilion AA

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Bacchetti S

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LeFeuvre CE

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P2860

The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

Human telomeres contain at least three types of G-rich repeat distributed non-randomly

A new technique for the assay of infectivity of human adenovirus 5 DNA

A mutant with a defect in telomere elongation leads to senescence in yeast.

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

Conservation of the human telomere sequence (TTAGGG)n among vertebrates

Telomeres shorten during ageing of human fibroblasts

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter

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5

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556651

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