P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation
about
DNA damage control: regulation and functions of checkpoint kinase 1Crucial roles of RSK in cell motility by catalysing serine phosphorylation of EphA2Novel regulation of checkpoint kinase 1: Is checkpoint kinase 1 a good candidate for anti-cancer therapy?Roles of Chk1 in cell biology and cancer therapyPI 3-kinase-dependent phosphorylation of Plk1-Ser99 promotes association with 14-3-3γ and is required for metaphase-anaphase transition.A novel mouse model for ataxia-telangiectasia with a N-terminal mutation displays a behavioral defect and a low incidence of lymphoma but no increased oxidative burden.Wild-type H- and N-Ras promote mutant K-Ras-driven tumorigenesis by modulating the DNA damage response.Inhibition of the PI3K/Akt/GSK3 pathway downstream of BCR/ABL, Jak2-V617F, or FLT3-ITD downregulates DNA damage-induced Chk1 activation as well as G2/M arrest and prominently enhances induction of apoptosis.The fork and the kinase: a DNA replication tale from a CHK1 perspective.Oncogenic BRAF(V600E) Induces Clastogenesis and UVB HypersensitivityCytokinetic Failure-induced Tetraploidy Develops into Aneuploidy, Triggering Skin Aging in Phosphovimentin-deficient Mice.Ndel1 suppresses ciliogenesis in proliferating cells by regulating the trichoplein-Aurora A pathway.Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cellsCandidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the checkpoint kinase CHK1Ras-activated RSK1 phosphorylates EBP50 to regulate its nuclear localization and promote cell proliferation.Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11.Pim kinases phosphorylate Chk1 and regulate its functions in acute myeloid leukemia.RSK promotes G2 DNA damage checkpoint silencing and participates in melanoma chemoresistance.The p90 ribosomal S6 kinase (RSK) inhibitor BI-D1870 prevents gamma irradiation-induced apoptosis and mediates senescence via RSK- and p53-independent accumulation of p21WAF1/CIP1.The G2 checkpoint-a node-based molecular switch.The kinase domain residue serine 173 of Schizosaccharomyces pombe Chk1 kinase is critical for the response to DNA replication stress.Targeting AXL and mTOR Pathway Overcomes Primary and Acquired Resistance to WEE1 Inhibition in Small-Cell Lung Cancer.
P2860
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P2860
P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@ast
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@en
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@en-gb
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@nl
type
label
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@ast
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@en
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@en-gb
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@nl
prefLabel
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@ast
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@en
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@en-gb
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@nl
P2093
P2860
P921
P356
P1476
P90 RSK arranges Chk1 in the n ...... rity during cell proliferation
@en
P2093
Kousuke Kasahara
Makoto Matsuyama
Masaki Inagaki
Yasushi Yatabe
Zhonghua Wang
P2860
P304
P356
10.1091/MBC.E11-10-0883
P407
P577
2012-04-01T00:00:00Z