about
Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicinP90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferationPhospho-tyrosine dependent protein-protein interaction networkNon-Invasive Methods to Monitor Mechanisms of Resistance to Tyrosine Kinase Inhibitors in Non-Small-Cell Lung Cancer: Where Do We Stand?Clinical significance of T cell metabolic reprogramming in cancerLin28 and let-7 in cell metabolism and cancerPI3K and AKT: Unfaithful Partners in CancerAdenoid cystic carcinoma: current therapy and potential therapeutic advances based on genomic profilingTargeting Apoptosis and Multiple Signaling Pathways with Icariside II in Cancer Cellsp38 MAPK and PI3K/AKT Signalling Cascades inParkinson's DiseaseNew and emerging factors in tumorigenesis: an overviewWhat a tangled web we weave: emerging resistance mechanisms to inhibition of the phosphoinositide 3-kinase pathwayObesity, metabolic dysregulation, and cancer: a growing concern and an inflammatory (and microenvironmental) issueInterplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingDeconvoluting the obesity and breast cancer link: secretome, soil and seed interactionsPhosphoinositides: tiny lipids with giant impact on cell regulationCancer cell metabolism: implications for therapeutic targetsSignaling cross-talk in the resistance to HER family receptor targeted therapyInvolvement of free radicals in breast cancerA Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell InvasionA Synthetic Polyphosphoinositide Headgroup Surrogate in Complex with SHIP2 Provides a Rationale for Drug DiscoveryDiscovery and SAR of Novel 2,3-Dihydroimidazo[1,2-c]quinazoline PI3K Inhibitors: Identification of Copanlisib (BAY 80-6946)Reprogramming of glucose metabolism in hepatocellular carcinoma: Progress and prospectsPITPNC1 Recruits RAB1B to the Golgi Network to Drive Malignant SecretionPhospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizationsSuppression of survival signalling pathways by the phosphatase PHLPPEGFR-TKI resistance in NSCLC patients: mechanisms and strategiesSustained proliferation in cancer: Mechanisms and novel therapeutic targetsPKCη/Rdx-driven phosphorylation of PDK1: a novel mechanism promoting cancer cell survival and permissiveness for parvovirus-induced lysisNovel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli CellsPotential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)SASH1 inhibits proliferation and invasion of thyroid cancer cells through PI3K/Akt signaling pathwaySHIP2 multiple functions: a balance between a negative control of PtdIns(3,4,5)P₃ level, a positive control of PtdIns(3,4)P₂ production, and intrinsic docking properties.Long Noncoding RNA GAS5, Which Acts as a Tumor Suppressor via microRNA 21, Regulates Cisplatin Resistance Expression in Cervical Cancer.A first-in-human phase I dose-escalation, pharmacokinetic, and pharmacodynamic evaluation of intravenous LY2090314, a glycogen synthase kinase 3 inhibitor, administered in combination with pemetrexed and carboplatin.Additive effects of cherlerythrine chloride combination with erlotinib in human non-small cell lung cancer cells.Leptin revisited: its mechanism of action and potential for treating diabetes.Cross-species proteomics reveals specific modulation of signaling in cancer and stromal cells by phosphoinositide 3-kinase (PI3K) inhibitorsDNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airwaysIdentification of inhibitors of inositol 5-phosphatases through multiple screening strategies.
P2860
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P2860
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Targeting the PI3K signaling pathway in cancer
@ast
Targeting the PI3K signaling pathway in cancer
@en
Targeting the PI3K signaling pathway in cancer
@nl
type
label
Targeting the PI3K signaling pathway in cancer
@ast
Targeting the PI3K signaling pathway in cancer
@en
Targeting the PI3K signaling pathway in cancer
@nl
prefLabel
Targeting the PI3K signaling pathway in cancer
@ast
Targeting the PI3K signaling pathway in cancer
@en
Targeting the PI3K signaling pathway in cancer
@nl
P2860
P3181
P1476
Targeting the PI3K signaling pathway in cancer
@en
P2093
Jeffrey A Engelman
P2860
P3181
P356
10.1016/J.GDE.2009.11.002
P407
P577
2010-02-01T00:00:00Z