A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling
about
A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathwaysPRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitryTargeting the Checkpoint to Kill Cancer CellsPharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapyFanconi anemia and the cell cycle: new perspectives on aneuploidyConditional inactivation of the DNA damage response gene Hus1 in mouse testis reveals separable roles for components of the RAD9-RAD1-HUS1 complex in meiotic chromosome maintenanceMineotaur: a tool for high-content microscopy screen sharing and visual analyticsHierarchical modularity and the evolution of genetic interactomes across species.DNA damage response genes and the development of cancer metastasisThe circadian clock in cancer development and therapyPhosphorylation of the cryptochrome 1 C-terminal tail regulates circadian period lengthCircadian proteins CLOCK and BMAL1 in the chromatoid body, a RNA processing granule of male germ cellsCore circadian protein CLOCK is a positive regulator of NF-κB-mediated transcriptionActivation of the ATR kinase by the RPA-binding protein ETAA1ETAA1 acts at stalled replication forks to maintain genome integritySuper-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formationDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMSUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathwayCHD7 expression predicts survival outcomes in patients with resected pancreatic cancer.Wrestling with Chromosomes: The Roles of SUMO During MeiosisCircadian gene variants in cancer.A gemcitabine sensitivity screen identifies a role for NEK9 in the replication stress responseFANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage responseZTF-8 interacts with the 9-1-1 complex and is required for DNA damage response and double-strand break repair in the C. elegans germline.The role of master regulators in the metabolic/transcriptional coupling in breast carcinomasBoth OsRecQ1 and OsRDR1 are required for the production of small RNA in response to DNA-damage in rice.Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.Regulation of DNA damage responses and cell cycle progression by hMOB2.An essential function for the ATR-activation-domain (AAD) of TopBP1 in mouse development and cellular senescence.Circadian clock, cancer, and chemotherapy.DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilizationWolf-Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damagePronecrotic mixed lineage kinase domain-like protein expression is a prognostic biomarker in patients with early-stage resected pancreatic adenocarcinoma.RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling.A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription FactorsTargeted mutations in the ATR pathway define agent-specific requirements for cancer cell growth and survivalRescue of replication failure by Fanconi anaemia proteins.Contributions of Rad9 to tumorigenesis.A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response.New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans
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P2860
A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
A DNA damage response screen i ...... ein required for ATR signaling
@ast
A DNA damage response screen i ...... ein required for ATR signaling
@en
A DNA damage response screen i ...... ein required for ATR signaling
@en-gb
A DNA damage response screen i ...... ein required for ATR signaling
@nl
type
label
A DNA damage response screen i ...... ein required for ATR signaling
@ast
A DNA damage response screen i ...... ein required for ATR signaling
@en
A DNA damage response screen i ...... ein required for ATR signaling
@en-gb
A DNA damage response screen i ...... ein required for ATR signaling
@nl
prefLabel
A DNA damage response screen i ...... ein required for ATR signaling
@ast
A DNA damage response screen i ...... ein required for ATR signaling
@en
A DNA damage response screen i ...... ein required for ATR signaling
@en-gb
A DNA damage response screen i ...... ein required for ATR signaling
@nl
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A DNA damage response screen i ...... ein required for ATR signaling
@en
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Cecilia Cotta-Ramusino
E Robert McDonald
J Wade Harper
Kristen Hurov
Mathew E Sowa
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P304
P3181
P356
10.1126/SCIENCE.1203430
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P577
2011-06-10T00:00:00Z