ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression
about
Every amino acid matters: essential contributions of histone variants to mammalian development and diseaseLoss of ATRX Suppresses Resolution of Telomere Cohesion to Control Recombination in ALT Cancer CellsATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichmentDecreased expression of the chromatin remodeler ATRX associates with melanoma progressionMacroH2A histone variants act as a barrier upon reprogramming towards pluripotencyHistone variants and epigenetics.Histone variants: dynamic punctuation in transcription.Histone variants: emerging players in cancer biology.The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas.MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition.Chromatin Remodelers: From Function to Dysfunction.MacroH2A1 and ATM Play Opposing Roles in Paracrine Senescence and the Senescence-Associated Secretory PhenotypeHistone H2A variants in nucleosomes and chromatin: more or less stable?The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.Chromatin structure in telomere dynamicsOne identity or more for telomeres?Dynamics of histone H3.3 deposition in proliferating and senescent cells reveals a DAXX-dependent targeting to PML-NBs important for pericentromeric heterochromatin organization.Alternative Lengthening of Telomeres is characterized by reduced compaction of telomeric chromatin.ATRX: the case of a peculiar chromatin remodeler.Organizing the genome with H2A histone variants.Macro domains as metabolite sensors on chromatin.Histone variants: key players of chromatin.Chromatin maintenance and dynamics in senescence: a spotlight on SAHF formation and the epigenome of senescent cells.Emerging roles of ATRX in cancer.Arabidopsis ATRX Modulates H3.3 Occupancy and Fine-Tunes Gene Expression.Histone variants and melanoma: facts and hypotheses.Mechanisms of Nucleosome Dynamics In Vivo.ATRX and DAXX: Mechanisms and Mutations.The histone variant H3.3 claims its place in the crowded scene of epigenetics.Herpes simplex virus is equipped with RNA- and protein-based mechanisms to repress expression of ATRX, an effector of intrinsic immunity.The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure.ATRX is a regulator of therapy induced senescence in human cells.The Role of ATRX in Glioma Biology.Histone MacroH2A1: A Chromatin Point of Intersection between Fasting, Senescence and Cellular Regeneration.Mechanistic understanding of the role of ATRX in senescence provides new insight for combinatorial therapies with CDK4 inhibitors.ATRX promotes gene expression by facilitating transcriptional elongation through guanine-rich coding regions.Effect of ATRX and G-Quadruplex Formation by the VNTR Sequence on α-Globin Gene Expression.Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.Mutant ATRX: uncovering a new therapeutic target for glioma.
P2860
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P2860
ATRX-mediated chromatin association of histone variant macroH2A1 regulates α-globin expression
description
2012 nî lūn-bûn
@nan
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
ATRX-mediated chromatin associ ...... regulates α-globin expression
@ast
ATRX-mediated chromatin associ ...... regulates α-globin expression
@en
ATRX-mediated chromatin associ ...... regulates α-globin expression
@en-gb
ATRX-mediated chromatin associ ...... regulates α-globin expression
@nl
type
label
ATRX-mediated chromatin associ ...... regulates α-globin expression
@ast
ATRX-mediated chromatin associ ...... regulates α-globin expression
@en
ATRX-mediated chromatin associ ...... regulates α-globin expression
@en-gb
ATRX-mediated chromatin associ ...... regulates α-globin expression
@nl
prefLabel
ATRX-mediated chromatin associ ...... regulates α-globin expression
@ast
ATRX-mediated chromatin associ ...... regulates α-globin expression
@en
ATRX-mediated chromatin associ ...... regulates α-globin expression
@en-gb
ATRX-mediated chromatin associ ...... regulates α-globin expression
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
ATRX-mediated chromatin associ ...... regulates α-globin expression
@en
P2093
Benjamin A Garcia
Chiara Vardabasso
Clemens Bönisch
Dan Hasson
Daniel Smeets
Emily Bernstein
Gary LeRoy
Kajan Ratnakumar
Luis F Duarte
P2860
P304
P3181
P356
10.1101/GAD.179416.111
P407
P577
2012-03-01T00:00:00Z