The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
about
RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitinationUbiquitin ligases in cholesterol metabolismFeedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axisStructure of a RING E3 ligase and ubiquitin-loaded E2 primed for catalysisBIRC7–E2 ubiquitin conjugate structure reveals the mechanism of ubiquitin transfer by a RING dimerAutoinhibition and phosphorylation-induced activation mechanisms of human cancer and autoimmune disease-related E3 protein Cbl-bRegulation of ubiquitin transfer by XIAP, a dimeric RING E3 ligaseLiver X receptors at the intersection of lipid metabolism and atherogenesisA C2HC zinc finger is essential for the RING-E2 interaction of the ubiquitin ligase RNF125IDOL stimulates clathrin-independent endocytosis and multivesicular body-mediated lysosomal degradation of the low-density lipoprotein receptor.The LXR-Idol axis differentially regulates plasma LDL levels in primates and miceRegulation of MDM2 E3 ligase activity by phosphorylation after DNA damage.FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors.Association of MYLIP rs3757354 SNP and several environmental factors with serum lipid levels in the Guangxi Bai Ku Yao and Han populations.Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR.Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake.Both K63 and K48 ubiquitin linkages signal lysosomal degradation of the LDL receptor.RP1-13D10.2 Is a Novel Modulator of Statin-Induced Changes in Cholesterol.The E3 ubiquitin ligase Idol controls brain LDL receptor expression, ApoE clearance, and Aβ amyloidosis.Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction.Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases.The E3 ubiquitin ligase IDOL regulates synaptic ApoER2 levels and is important for plasticity and learning.Foiling IDOL to Help Control Cholesterol.Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms.CNPY2 inhibits MYLIP-mediated AR protein degradation in prostate cancer cells.InterEvDock2: an expanded server for protein docking using evolutionary and biological information from homology models and multimeric inputs.
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P2860
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@ast
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@en
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@en-gb
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@nl
type
label
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@ast
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@en
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@en-gb
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@nl
prefLabel
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@ast
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@en
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@en-gb
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@nl
P2093
P2860
P50
P921
P3181
P356
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P1476
The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor
@en
P2093
Benjamin T Goult
Cynthia Hong
John W R Schwabe
P2860
P304
P3181
P356
10.1101/GAD.2056211
P407
P577
2011-06-15T00:00:00Z