The human PAF complex coordinates transcription with events downstream of RNA synthesis.
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Chromatin landscape dictates HSF binding to target DNA elementsWAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcriptionTranscriptional activators enhance polyadenylation of mRNA precursorsThe Spt6 SH2 domain binds Ser2-P RNAPII to direct Iws1-dependent mRNA splicing and exportHuman RNA polymerase II-association factor 1 (hPaf1/PD2) regulates histone methylation and chromatin remodeling in pancreatic cancerThe human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIISThe parafibromin tumor suppressor protein inhibits cell proliferation by repression of the c-myc proto-oncogeneThe tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factorsThe PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesisc-Myc regulates transcriptional pause releaseDOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cellsMammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genesSyndromic diarrhea/Tricho-hepato-enteric syndromeProteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsArabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control floral transition and plant developmentStructural insights into Paf1 complex assembly and histone bindingStructural basis for Spt5-mediated recruitment of the Paf1 complex to chromatinRtf1 is a multifunctional component of the Paf1 complex that regulates gene expression by directing cotranscriptional histone modification.Effects of the Paf1 complex and histone modifications on snoRNA 3'-end formation reveal broad and locus-specific regulation.The Paf1 complex is required for efficient transcription elongation by RNA polymerase IDirect interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.The RNA polymerase-associated factor 1 complex (Paf1C) directly increases the elongation rate of RNA polymerase I and is required for efficient regulation of rRNA synthesis.A Requirement for the Saccharomyces cerevisiae Paf1 complex in snoRNA 3' end formationLeo1 subunit of the yeast paf1 complex binds RNA and contributes to complex recruitment.Context-dependent dual role of SKI8 homologs in mRNA synthesis and turnoverHistone and DNA methylation defects at Hox genes in mice expressing a SET domain-truncated form of Mll.hCTR9, a component of Paf1 complex, participates in the transcription of interleukin 6-responsive genes through regulation of STAT3-DNA interactionsParafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult miceRegulation of MLL1 H3K4 methyltransferase activity by its core componentsMultiple yeast genes, including Paf1 complex genes, affect telomere length via telomerase RNA abundanceA lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency.A comprehensive library of histone mutants identifies nucleosomal residues required for H3K4 methylation.Genic and global functions for Paf1C in chromatin modification and gene expression in Arabidopsis.The human RNA polymerase II-associated factor 1 (hPaf1): a new regulator of cell-cycle progression.The tumor suppressor, parafibromin, mediates histone H3 K9 methylation for cyclin D1 repression.Integrated analysis of recurrent properties of cancer genes to identify novel driversRNA polymerase II associated factor 1/PD2 maintains self-renewal by its interaction with Oct3/4 in mouse embryonic stem cellsNovel role of pancreatic differentiation 2 in facilitating self-renewal and drug resistance of pancreatic cancer stem cells.PD2/Paf1 depletion in pancreatic acinar cells promotes acinar-to-ductal metaplasia.Drosophila Paf1 modulates chromatin structure at actively transcribed genes.
P2860
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P248
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P2860
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
The human PAF complex coordinates transcription with events downstream of RNA synthesis
@nl
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@ast
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@en
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@en-gb
type
label
The human PAF complex coordinates transcription with events downstream of RNA synthesis
@nl
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@ast
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@en
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@en-gb
prefLabel
The human PAF complex coordinates transcription with events downstream of RNA synthesis
@nl
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@ast
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@en
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@en-gb
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
The human PAF complex coordinates transcription with events downstream of RNA synthesis.
@en
P2093
Anh-Dung Pham
Surinder K Batra
Yong Zheng
P2860
P304
P3181
P356
10.1101/GAD.1292105
P407
P577
2005-07-01T00:00:00Z