Regulation of MLL1 H3K4 methyltransferase activity by its core components - Test2 - elhamkhani - TriplyDB

Regulation of MLL1 H3K4 methyltransferase activity by its core components

Regulation of MLL1 H3K4 methyltransferase activity by its core components

http://www.wikidata.org/entity/Q29614518

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Proteasome inhibitors evoke latent tumor suppression programs in pro-B MLL leukemias through MLL-AF4 Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8 Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex Wdr82 is a C-terminal domain-binding protein that recruits the Setd1A Histone H3-Lys4 methyltransferase complex to transcription start sites of transcribed human genes Contribution of H3K4 methylation by SET-1A to interleukin-1-induced cyclooxygenase 2 and inducible nitric oxide synthase expression in human osteoarthritis chondrocytes PRMT6-mediated methylation of R2 in histone H3 antagonizes H3 K4 trimethylation PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53 CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression Molecular regulation of H3K4 trimethylation by Wdr82, a component of human Set1/COMPASS A role of histone H3 lysine 4 methyltransferase components in endosomal trafficking Knockdown of ALR (MLL2) reveals ALR target genes and leads to alterations in cell adhesion and growth.On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers Dimerization of a viral SET protein endows its function Cellular senescence and tumor suppressor gene p16 Mammalian ASH1L is a histone methyltransferase that occupies the transcribed region of active genes The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth Systematic Classification of Mixed-Lineage Leukemia Fusion Partners Predicts Additional Cancer Pathways Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia Mechanisms of epigenetic regulation of leukemia onset and progression Histone methylation makes its mark on longevity Hijacked in cancer: the KMT2 (MLL) family of methyltransferases On WD40 proteins: propelling our knowledge of transcriptional control?Mll5 is required for normal spermatogenesis Regulation of DCC localization by HTZ-1/H2A.Z and DPY-30 does not correlate with H3K4 methylation levels A role for Set1/MLL-related components in epigenetic regulation of the Caenorhabditis elegans germ line Arabidopsis COMPASS-like complexes mediate histone H3 lysine-4 trimethylation to control floral transition and plant development Structural origins for the product specificity of SET domain protein methyltransferases Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1 Crystal structure of the trithorax group protein ASH2L reveals a forkhead-like DNA binding domain Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation Symmetric dimethylation of H3R2 is a newly identified histone mark that supports euchromatin maintenance Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30 The plasticity of WDR5 peptide-binding cleft enables the binding of the SET1 family of histone methyltransferases Structural Basis for WDR5 Interaction (Win) Motif Recognition in Human SET1 Family Histone Methyltransferases High-affinity, small-molecule peptidomimetic inhibitors of MLL1/WDR5 protein-protein interaction

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

http://www.wikidata.org/entity/Q29614518

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2006 nî lūn-bûn

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2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2006 թվականի օգոստոսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

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prefLabel

Regulation of MLL1 H3K4 methyltransferase activity by its core components

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

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Nature Structural & Molecular Biology

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Regulation of MLL1 H3K4 methyltransferase activity by its core components

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P2093

Allis CD

http://www.w3.org/2001/XMLSchema#string

Dou Y

http://www.w3.org/2001/XMLSchema#string

Lee JW

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Lee S

http://www.w3.org/2001/XMLSchema#string

Milne TA

http://www.w3.org/2001/XMLSchema#string

Roeder RG

http://www.w3.org/2001/XMLSchema#string

Ruthenburg AJ

http://www.w3.org/2001/XMLSchema#string

Verdine GL

http://www.w3.org/2001/XMLSchema#string

P2860

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

The human homolog of yeast BRE1 functions as a transcriptional coactivator through direct activator interactions

Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1

Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

The human PAF complex coordinates transcription with events downstream of RNA synthesis.

Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus

Structural basis for the specific recognition of methylated histone H3 lysine 4 by the WD-40 protein WDR5

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4

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713-9

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scholarly article

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566162

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10.1038/NSMB1128

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8

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13

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2006-08-01T00:00:00Z

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6908754

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1047968845

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16878130

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