HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerLabel-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methodsSystematic analysis of human protein complexes identifies chromosome segregation proteinsCAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM componentsThe Ran Pathway in Drosophila melanogaster MitosisAugmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscissionIdentification of the augmin complex in the filamentous fungus Aspergillus nidulansMeiosis-specific stable binding of augmin to acentrosomal spindle poles promotes biased microtubule assembly in oocytesNon-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity.Pooled-matrix protein interaction screens using Barcode Fusion GeneticsA Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium InterfaceTranscriptional program of ciliated epithelial cells reveals new cilium and centrosome components and links to human diseaseγ-Tubulin Ring Complexes and EB1 play antagonistic roles in microtubule dynamics and spindle positioningDiffering requirements for Augmin in male meiotic and mitotic spindle formation in Drosophila.Augmin plays a critical role in organizing the spindle and phragmoplast microtubule arrays in Arabidopsis.Characterization of the Arabidopsis augmin complex uncovers its critical function in the assembly of the acentrosomal spindle and phragmoplast microtubule arrays.Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-tubulin ring complex to the mitotic spindleHigh resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.Automatic quantification of microtubule dynamics enables RNAi-screening of new mitotic spindle regulators.Deep proteomics of the Xenopus laevis egg using an mRNA-derived reference databaseThe elegans of spindle assembly.Mechanisms promoting escape from mitotic stress-induced tumor cell death.Mutations in centrosomal protein CEP152 in primary microcephaly families linked to MCPH4.Cyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly.Clinical implications of next-generation sequencing for cancer medicine.Functional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase.The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8Branching microtubule nucleation in Xenopus egg extracts mediated by augmin and TPX2.Weighted frequent gene co-expression network mining to identify genes involved in genome stability.A potential role for NEDD1 and the centrosome in senescence of mouse embryonic fibroblasts.Reconstitution of the augmin complex provides insights into its architecture and function.Mapping the cellular response to small molecules using chemogenomic fitness signatures.Regulation of microtubule-based microtubule nucleation by mammalian polo-like kinase 1.The function of mammalian Polo-like kinase 1 in microtubule nucleation.Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extractsAurora-A phosphorylates Augmin complex component Hice1 protein at an N-terminal serine/threonine cluster to modulate its microtubule binding activity during spindle assembly.Emergent Properties of the Metaphase Spindle.Decoding the evolution of a breast cancer genome
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HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
description
2009 nî lūn-bûn
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2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
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2009 թվականի մայիսին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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name
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@ast
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@en
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@en-gb
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
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type
label
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@ast
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@en
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@en-gb
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@nl
prefLabel
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@ast
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@en
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@en-gb
HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@nl
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P50
P921
P3181
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HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity
@en
P2093
Andrea Tagliaferro
Deborah Pinchev
James R A Hutchins
Laurence Pelletier
Mariana Gomez Ferreria
Michael Mullin
Mikhail Bashkurov
Steffen Lawo
P304
P3181
P356
10.1016/J.CUB.2009.04.033
P407
P50
P577
2009-05-26T00:00:00Z