Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components
about
Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerImportance of the CEP215-pericentrin interaction for centrosome maturation during mitosisA direct interaction with NEDD1 regulates gamma-tubulin recruitment to the centrosomeThe novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolusConserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complexCross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle AssemblyInterphase centrosome organization by the PLP-Cnn scaffold is required for centrosome functionMLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1Multiple requirements of PLK1 during mouse oocyte maturationA CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancerCentrosome - a promising anti-cancer targetA unique set of centrosome proteins requires pericentrin for spindle-pole localization and spindle orientationA mechanism for the elimination of the female gamete centrosome in Drosophila melanogasterBod1 regulates protein phosphatase 2A at mitotic kinetochoresNek2 phosphorylates and stabilizes β-catenin at mitotic centrosomes downstream of Plk1.Excess centrosomes disrupt endothelial cell migration via centrosome scattering.Pericentrin in cellular function and diseasePrimary microcephaly: do all roads lead to Rome?CDK5RAP2 functions in centrosome to spindle pole attachment and DNA damage response.CDK11(p58) is required for centriole duplication and Plk4 recruitment to mitotic centrosomes.Quantitative proteomics combined with BAC TransgeneOmics reveals in vivo protein interactionsOrganelle asymmetry for proper fitness, function, and fateDrosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodiesA molecular mechanism of mitotic centrosome assembly in DrosophilaSeparase-dependent cleavage of pericentrin B is necessary and sufficient for centriole disengagement during mitosis.The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8Coiled-coil domain containing protein 124 is a novel centrosome and midbody protein that interacts with the Ras-guanine nucleotide exchange factor 1B and is involved in cytokinesis.The Plk1-dependent phosphoproteome of the early mitotic spindleThe Cep192-organized aurora A-Plk1 cascade is essential for centrosome cycle and bipolar spindle assembly.p38α MAPK is a MTOC-associated protein regulating spindle assembly, spindle length and accurate chromosome segregation during mouse oocyte meiotic maturation.Polo-like kinases (plks), a key regulator of cell cycle and new potential target for cancer therapy.Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis.The centrosome and its duplication cycleThe function of mammalian Polo-like kinase 1 in microtubule nucleation.The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation.Sensors at centrosomes reveal determinants of local separase activity.Quantitative immunofluorescence assay to measure the variation in protein levels at centrosomes.Degradation of Cep68 and PCNT cleavage mediate Cep215 removal from the PCM to allow centriole separation, disengagement and licensing.PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis.Integrins regulate microtubule nucleating activity of centrosome through mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signaling.
P2860
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P2860
Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components
description
2009 nî lūn-bûn
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2009 թուականին հրատարակուած գիտական յօդուած
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2009 թվականին հրատարակված գիտական հոդված
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2009年の論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年論文
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2009年论文
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name
Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
@ast
Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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Plk1-dependent recruitment of ...... volves multiple PCM components
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P2860
P921
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P1476
Plk1-dependent recruitment of ...... volves multiple PCM components
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P2093
Laurence Haren
P2860
P3181
P356
10.1371/JOURNAL.PONE.0005976
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P577
2009-06-19T00:00:00Z