Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
about
The roles of ASK family proteins in stress responses and diseasesThe RAF inhibitor PLX4032 inhibits ERK signaling and tumor cell proliferation in a V600E BRAF-selective mannerDRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosisJNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extensionJSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathwayPSK, a novel STE20-like kinase derived from prostatic carcinoma that activates the c-Jun N-terminal kinase mitogen-activated protein kinase pathway and regulates actin cytoskeletal organizationGene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent streMAPK upstream kinase (MUK)-binding inhibitory protein, a negative regulator of MUK/dual leucine zipper-bearing kinase/leucine zipper protein kinaseReactive oxygen species-activated Akt/ASK1/p38 signaling pathway in nickel compound-induced apoptosis in BEAS 2B cellsAkt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1Identification and characterization of functional domains in a mixed lineage kinase LZKApoptosis signal-regulating kinase 1 controls the proapoptotic function of death-associated protein (Daxx) in the cytoplasmInvolvement of alpha-PAK-interacting exchange factor in the PAK1-c-Jun NH(2)-terminal kinase 1 activation and apoptosis induced by benzo[a]pyreneMRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrestType 1 insulin-like growth factor receptor (IGF-IR) signaling inhibits apoptosis signal-regulating kinase 1 (ASK1)Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activationScaffold role of a mitogen-activated protein kinase phosphatase, SKRP1, for the JNK signaling pathwayNoxa is necessary for hydrogen peroxide-induced caspase-dependent cell deathThe endoplasmic reticulum stress response in aging and age-related diseasesASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeatsProstate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activationAIP1/DAB2IP, a novel member of the Ras-GAP family, transduces TRAF2-induced ASK1-JNK activationThioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf miceAIP1 mediates TNF-alpha-induced ASK1 activation by facilitating dissociation of ASK1 from its inhibitor 14-3-3Positive regulation of apoptosis signal-regulating kinase 1 by hD53L1Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathwaysExecution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alphaAIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress responseZIP kinase, a novel serine/threonine kinase which mediates apoptosisZIP kinase triggers apoptosis from nuclear PML oncogenic domainsPositive regulation of apoptosis signal-regulating kinase 1 signaling by ZPR9 protein, a zinc finger proteinDAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosisDaxx, a novel Fas-binding protein that activates JNK and apoptosisHuman glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signalsRoquin-2 promotes ubiquitin-mediated degradation of ASK1 to regulate stress responsesCIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1Direct interaction and reciprocal regulation between ASK1 and calcineurin-NFAT control cardiomyocyte death and growthMicrospherule protein 2 associates with ASK1 and acts as a negative regulator of stress-induced ASK1 activation
P2860
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P2860
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
description
1997 nî lūn-bûn
@nan
1997 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@ast
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@en
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@en-gb
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@nl
type
label
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@ast
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@en
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@en-gb
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@nl
prefLabel
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@ast
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@en
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@en-gb
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@nl
P2093
P921
P3181
P1433
P1476
Induction of apoptosis by ASK1 ...... JNK and p38 signaling pathways
@en
P2093
K Matsumoto
K Miyazono
P ten Dijke
P3181
P356
10.1126/SCIENCE.275.5296.90
P407
P577
1997-01-03T00:00:00Z