Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini
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RSK-B, a novel ribosomal S6 kinase family member, is a CREB kinase under dominant control of p38alpha mitogen-activated protein kinase (p38alphaMAPK)Molecular cloning and characterization of a novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich regionRegulation and localization of ribosomal protein S6 kinase 1 isoformsMutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1Relatedness of an RNA-binding motif in human immunodeficiency virus type 1 TAR RNA-binding protein TRBP to human P1/dsI kinase and Drosophila staufenUp-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's diseaseLeaky ribosomal scanning in mammalian genomes: significance of histone H4 alternative translation in vivoStructural Basis of Human p70 Ribosomal S6 Kinase-1 Regulation by Activation Loop PhosphorylationCrystal structures of the S6K1 kinase domain in complexes with inhibitorsAnalysis of a binding difference between the two dsRNA-binding domains in TRBP reveals the modular function of a KR-helix motifCharacterization of S6K2, a novel kinase homologous to S6K1Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alphamTOR signaling in tumorigenesisAmino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanismIdentification of the S6 kinase activity stimulated in quiescent brine shrimp embryos upon entry to preemergence development as p70 ribosomal protein S6 kinase: isolation of Artemia franciscana p70S6k cDNA.A single gene encodes two isoforms of the p70 S6 kinase: activation upon mitogenic stimulation.Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal.Insulin promotes rat retinal neuronal cell survival in a p70S6K-dependent manner.Cross-talk between sirtuin and mammalian target of rapamycin complex 1 (mTORC1) signaling in the regulation of S6 kinase 1 (S6K1) phosphorylation.Structural and functional analysis of pp70S6k.Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase.Control sites of ribosomal S6 kinase B and persistent activation through tumor necrosis factor.Identification and early activation of a Xenopus laevis p70s6k following progesterone-induced meiotic maturation.Role of MLK3-mediated activation of p70 S6 kinase in Rac1 transformation.Heterogeneous expression of four MAP kinase isoforms in human tissues.Phosphatidylinositol 3-kinase signals activation of p70 S6 kinase in situ through site-specific p70 phosphorylationRibosomal p70S6K basal activity increases upon induction of differentiation of myelomonocytic leukemic cell lines HL60, AML14 and MPDPhospholipase D regulates myogenic differentiation through the activation of both mTORC1 and mTORC2 complexes.Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).Revealing Different Roles of the mTOR-Targets S6K1 and S6K2 in Breast Cancer by Expression Profiling and Structural Analysis.A Drosophila gene structurally and functionally homologous to the mammalian 70-kDa s6 kinase gene.Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity.Baculovirus-mediated expression, purification, and characterization of a fully activated catalytic kinase domain construct of the 70 kDa 40S ribosomal protein S6 kinase-1 alphaII isoform (S6K1alphaII).Expression, purification, and characterization of a structurally disordered and functional C-terminal autoinhibitory domain (AID) of the 70 kDa 40S ribosomal protein S6 kinase-1 (S6K1).Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cyclic AMP.Overexpression of P70 S6 kinase protein is associated with increased risk of locoregional recurrence in node-negative premenopausal early breast cancer patients.eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling.The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancerActivation of p70s6k is associated with phosphorylation of four clustered sites displaying Ser/Thr-Pro motifsInterleukin 2 stimulation of p70 S6 kinase activity is inhibited by the immunosuppressant rapamycin.
P2860
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P2860
Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino termini
description
1991 nî lūn-bûn
@nan
1991 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Cloning and expression of two ...... ng only at their amino termini
@ast
Cloning and expression of two ...... ng only at their amino termini
@en
Cloning and expression of two ...... ng only at their amino termini
@en-gb
Cloning and expression of two ...... ng only at their amino termini
@nl
type
label
Cloning and expression of two ...... ng only at their amino termini
@ast
Cloning and expression of two ...... ng only at their amino termini
@en
Cloning and expression of two ...... ng only at their amino termini
@en-gb
Cloning and expression of two ...... ng only at their amino termini
@nl
prefLabel
Cloning and expression of two ...... ng only at their amino termini
@ast
Cloning and expression of two ...... ng only at their amino termini
@en
Cloning and expression of two ...... ng only at their amino termini
@en-gb
Cloning and expression of two ...... ng only at their amino termini
@nl
P2093
P2860
P921
P356
P1476
Cloning and expression of two ...... ng only at their amino termini
@en
P2093
A Balasubramanyam
J R Woodgett
P Banerjee
P J Coffer
P2860
P304
P356
10.1128/MCB.11.11.5541
P407
P577
1991-11-01T00:00:00Z