about
P688
The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activityS6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signalingmTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4ERaptor, a binding partner of target of rapamycin (TOR), mediates TOR actionS6K directly phosphorylates IRS-1 on Ser-270 to promote insulin resistance in response to TNF-(alpha) signaling through IKK2Cloning and expression of two human p70 S6 kinase polypeptides differing only at their amino terminiSKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAsPhosphorylation and activation of p70s6k by PDK1EPRS is a critical mTORC1-S6K1 effector that influences adiposity in mice.Mammalian EAK-7 activates alternative mTOR signaling to regulate cell proliferation and migration.
P921
Q24293101-D5F25BFB-FB80-41DD-AADA-F31CCCAB0496Q24297650-31E9396D-9029-4643-87FA-59F4C71FDE4DQ24301780-3DCD9091-6A14-4E1E-B566-473F3E12EE85Q24302566-B3AF7DF4-2A5D-49AE-A255-03538AE2C0FDQ24309036-28AD13F5-BC68-4C05-9F02-FF9A984DF30BQ24311546-B1F0CB25-700D-434D-9285-C1155F75B66AQ24323236-745BE9E3-91F1-4AE0-85F0-6051A8DBEAE8Q24323433-85AAFE45-2293-4F0A-B0F5-329C590931CDQ41068541-DA3B4518-5933-43C1-BF37-4477F51A48A8Q54943035-A99B591D-DC48-42F4-82D5-270A42BCB01F
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in Ribosomal protein S6 kinase B1
@nl
protèin
@ace
بروتين في الإنسان العاقل
@ar
name
Ribosomal protein S6 kinase B1
@en
type
label
Ribosomal protein S6 kinase B1
@en
altLabel
70 kDa ribosomal protein S6 kinase 1
@en
P70S6K1
@en
RPS6KB1
@en
p70 S6 kinase alpha
@en
p70 S6 kinase, alpha
@en
p70 S6K-alpha
@en
p70 S6KA
@en
p70 ribosomal S6 kinase alpha
@en
p70-S6K 1
@en
ribosomal protein S6 kinase I
@en
prefLabel
Ribosomal protein S6 kinase B1
@en
P527
P637
P638
P680
P681
P682
P705
P352
P637
P31
P352
P527
P637
NP_001258971
NP_001258972
NP_001258973
NP_001258989
NP_001356598
NP_001356599
NP_001356600
NP_001356601
NP_001356602
NP_001356603
P638
P680
P681
P682
P702
P703
P705
ENSP00000225577
ENSP00000376744
ENSP00000384335
ENSP00000441993
ENSP00000464805
ENSP00000466562
ENSP00000468058