about
Clinical significance of T cell metabolic reprogramming in cancerThe mTOR pathway in obesity driven gastrointestinal cancers: Potential targets and clinical trialsEvolutionary Limitation and Opportunities for Developing tRNA Synthetase Inhibitors with 5-Binding-Mode ClassificationPredictive and prognostic biomarkers of targeted agents and modern immunotherapy in renal cell carcinomaRegulation of Ketone Body Metabolism and the Role of PPARαFAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistancemTOR activation is a biomarker and a central pathway to autoimmune disorders, cancer, obesity, and agingHER2-positive breast cancer cells expressing elevated FAM83A are sensitive to FAM83A loss.Insulin Increases Sestrin 2 Content by Reducing Its Degradation through the PI 3 K/mTOR Signaling Pathway.SC06, a novel small molecule compound, displays preclinical activity against multiple myeloma by disrupting the mTOR signaling pathwayα-Mangostin, a Natural Agent, Enhances the Response of NRAS Mutant Melanoma to Retinoic Acid.Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.N-Hydroxyphthalimide exhibits antitumor activity by suppressing mTOR signaling pathway in BT-20 and LoVo cells.The Transcription Factor p8 Regulates Autophagy in Response to Palmitic Acid Stress via a Mammalian Target of Rapamycin (mTOR)-independent Signaling PathwayDual mTOR inhibitor MLN0128 suppresses Merkel cell carcinoma (MCC) xenograft tumor growth.Genetics of tuberous sclerosis complex: implications for clinical practiceEverolimus is better than rapamycin in attenuating neuroinflammation in kainic acid-induced seizures.mTOR function and therapeutic targeting in breast cancer.Pleurotus nebrodensis polysaccharide(PN50G) evokes A549 cell apoptosis by the ROS/AMPK/PI3K/AKT/mTOR pathway to suppress tumor growth.Oncogenic and tumor-suppressive mouse models for breast cancer engaging HER2/neu.Diverse Immunoprofile of Ductal Adenocarcinoma of the Prostate with an Emphasis on the Prognostic Factors.Spheroid growth in ovarian cancer alters transcriptome responses for stress pathways and epigenetic responses.Transforming somatic mutations of mammalian target of rapamycin kinase in human cancer.Molecular Profiling of Thymoma and Thymic Carcinoma: Genetic Differences and Potential Novel Therapeutic TargetsRheb may complex with RASSF1A to coordinate Hippo and TOR signaling.Inhibition of mTORC2 component RICTOR impairs tumor growth in pancreatic cancer models.mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer.Inhibition of Rb Phosphorylation Leads to mTORC2-Mediated Activation of Akt.Inducible CRISPR genome-editing tool: classifications and future trends.Acquired resistance to PI3K/mTOR inhibition is associated with mitochondrial DNA mutation and glycolysis.Targeted therapy of gastroenteropancreatic neuroendocrine tumours: preclinical strategies and future targets.Dosing time dependent in vitro pharmacodynamics of Everolimus despite a defective circadian clock.GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.Starving cancer from the outside and inside: separate and combined effects of calorie restriction and autophagy inhibition on Ras-driven tumors.Meta-analysis of the prognostic value of p-4EBP1 in human malignancies.Genetic Variants Within MTORC1 Genes Predict Gastric Cancer Prognosis in Chinese Populations.Hypoxic Signalling in Tumour Stroma.Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast CancerRegnase-1 controls colon epithelial regeneration via regulation of mTOR and purine metabolismURI knockdown induces autophagic flux in gastric cancer cells
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
mTOR signaling in tumorigenesis
@ast
mTOR signaling in tumorigenesis
@en
mTOR signaling in tumorigenesis
@nl
type
label
mTOR signaling in tumorigenesis
@ast
mTOR signaling in tumorigenesis
@en
mTOR signaling in tumorigenesis
@nl
prefLabel
mTOR signaling in tumorigenesis
@ast
mTOR signaling in tumorigenesis
@en
mTOR signaling in tumorigenesis
@nl
P2093
P2860
P3181
P1476
mTOR signaling in tumorigenesis
@en
P2093
P2860
P304
P3181
P356
10.1016/J.BBCAN.2014.10.007
P407
P577
2014-12-01T00:00:00Z