Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging
about
Human ZMPSTE24 disease mutations: residual proteolytic activity correlates with disease severityDNA Damage: A Main Determinant of Vascular AgingMechanisms of arterial calcifications and consequences for cardiovascular functionMouse models of laminopathiesAging and longevity in the simplest animals and the quest for immortalityNuclear lamins and oxidative stress in cell proliferation and longevityThe structural basis of ZMPSTE24-dependent laminopathiesNADPH oxidases: key modulators in aging and age-related cardiovascular diseases?Age-associated pro-inflammatory remodeling and functional phenotype in the heart and large arteriesCellular and molecular biology of aging endothelial cellsAging and radiation: bad companionsThe hallmarks of agingPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesEmbryonic senescence and laminopathies in a progeroid zebrafish modelCalcific aortic valve stenosis: methods, models, and mechanismsNon-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.Site-Specific Secretome Map Evidences VSMC-Related Markers of Coronary Atherosclerosis Grade and Extent in the Hypercholesterolemic Swine.Prelamin A accumulation and stress conditions induce impaired Oct-1 activity and autophagy in prematurely aged human mesenchymal stem cellMechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1.HIV protease inhibitor exposure predicts cerebral small vessel disease.Differential temporal and spatial progerin expression during closure of the ductus arteriosus in neonatesAn improved isoprenylcysteine carboxylmethyltransferase inhibitor induces cancer cell death and attenuates tumor growth in vivo.DNA-damage accumulation and replicative arrest in Hutchinson-Gilford progeria syndromeFunctional coupling between the extracellular matrix and nuclear lamina by Wnt signaling in progeria.Requirements for efficient proteolytic cleavage of prelamin A by ZMPSTE24.Cell autonomous and systemic factors in progeria development.Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.Accelerating neuronal aging in in vitro model brain disorders: a focus on reactive oxygen speciesRapamycin treatment of Mandibuloacral dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamicsHIV protease inhibitors do not cause the accumulation of prelamin A in PBMCs from patients receiving first line therapy: the ANRS EP45 "aging" studyRecapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndromeThe roles of lipid oxidation products and receptor activator of nuclear factor-κB signaling in atherosclerotic calcificationHistone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient miceAntisense oligonucleotide induction of progerin in human myogenic cells'Relax and Repair' to restrain aging.MicroRNA transcriptome analysis identifies miR-365 as a novel negative regulator of cell proliferation in Zmpste24-deficient mouse embryonic fibroblasts.Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome.The role of nuclear lamin B1 in cell proliferation and senescence.Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageingPoly(ADP-ribose) protects vascular smooth muscle cells from oxidative DNA damage.
P2860
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P2860
Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Prelamin A acts to accelerate ...... marker of human vascular aging
@ast
Prelamin A acts to accelerate ...... marker of human vascular aging
@en
Prelamin A acts to accelerate ...... marker of human vascular aging
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Prelamin A acts to accelerate ...... marker of human vascular aging
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type
label
Prelamin A acts to accelerate ...... marker of human vascular aging
@ast
Prelamin A acts to accelerate ...... marker of human vascular aging
@en
Prelamin A acts to accelerate ...... marker of human vascular aging
@en-gb
Prelamin A acts to accelerate ...... marker of human vascular aging
@nl
prefLabel
Prelamin A acts to accelerate ...... marker of human vascular aging
@ast
Prelamin A acts to accelerate ...... marker of human vascular aging
@en
Prelamin A acts to accelerate ...... marker of human vascular aging
@en-gb
Prelamin A acts to accelerate ...... marker of human vascular aging
@nl
P2093
P921
P3181
P1433
P1476
Prelamin A acts to accelerate ...... marker of human vascular aging
@en
P2093
Cassandra D Ragnauth
Derek T Warren
Jeremy Skepper
Nichola Figg
Rosamund McNair
Rukshana Shroff
Tamara Tajsic
P304
P3181
P356
10.1161/CIRCULATIONAHA.109.902056
P407
P577
2010-05-10T00:00:00Z