DNA nucleotide excision repair-dependent signaling to checkpoint activation
about
Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repairThe role of altered nucleotide excision repair and UVB-induced DNA damage in melanomagenesisInvolvement of nucleotide excision and mismatch repair mechanisms in double strand break repairTwo faces of p53: aging and tumor suppressionNucleotide excision repair in eukaryotesThe DNA Damage Response: Making It Safe to Play with KnivesDNA IR-Double Strand Breaks (DSBs) and cellular response via ATMReplication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair.The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2.On the traces of XPD: cell cycle matters - untangling the genotype-phenotype relationship of XPD mutationsA protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening.NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sitesCheckpoint kinase ATR phosphorylates Cdt2, a substrate receptor of CRL4 ubiquitin ligase, and promotes the degradation of Cdt1 following UV irradiation.The structural determinants of checkpoint activationRegulators of global genome repair do not respond to DNA damaging therapy but correlate with survival in melanoma.NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegansHuman exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation.The rem mutations in the ATP-binding groove of the Rad3/XPD helicase lead to Xeroderma pigmentosum-Cockayne syndrome-like phenotypes.Mitotic UV irradiation induces a DNA replication-licensing defect that potentiates G1 arrest response.Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylationReconstitution of a human ATR-mediated checkpoint response to damaged DNA.RNA polymerase: the most specific damage recognition protein in cellular responses to DNA damage?Nucleotide excision repair deficiency increases levels of acrolein-derived cyclic DNA adduct and sensitizes cells to apoptosis induced by docosahexaenoic acid and acrolein.Induction of a G1-S checkpoint in fission yeastDevelopment of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression.Bringing It All Together: Coupling Excision Repair to the DNA Damage Checkpoint.DNA excision repair: where do all the dimers go?ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress.The coregulator AlienCooperative activation of the ATR checkpoint kinase by TopBP1 and damaged DNA.DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases.A tale of two tails: activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1.Telomere attrition and genomic instability in xeroderma pigmentosum type-b deficient fibroblasts under oxidative stressHuman SNF5/INI1, a component of the human SWI/SNF chromatin remodeling complex, promotes nucleotide excision repair by influencing ATM recruitment and downstream H2AX phosphorylationThe unstructured C-terminal tail of the 9-1-1 clamp subunit Ddc1 activates Mec1/ATR via two distinct mechanisms.Coupling of human DNA excision repair and the DNA damage checkpoint in a defined in vitro system.The Intra-S Checkpoint Responses to DNA Damage.Mind the gap: keeping UV lesions in check.
P2860
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P2860
DNA nucleotide excision repair-dependent signaling to checkpoint activation
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@ast
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@en
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@en-gb
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@nl
type
label
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@ast
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@en
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@en-gb
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@nl
prefLabel
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@ast
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@en
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@en-gb
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
DNA nucleotide excision repair-dependent signaling to checkpoint activation
@en
P2093
Mario Minuzzo
Miria Stefanini
Tiziana Nardo
P2860
P304
17325-17330
P3181
P356
10.1073/PNAS.0605446103
P407
P577
2006-11-06T00:00:00Z