PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
about
Phosphorylation- and polo-box-dependent binding of Plk1 to Bub1 is required for the kinetochore localization of Plk1The hsSsu72 phosphatase is a cohesin-binding protein that regulates the resolution of sister chromatid arm cohesionp31comet blocks Mad2 activation through structural mimicryTripin/hSgo2 recruits MCAK to the inner centromere to correct defective kinetochore attachmentsThe acetyltransferase activity of San stabilizes the mitotic cohesin at the centromeres in a shugoshin-independent mannerShugoshin is a Mad1/Cdc20-like interactor of Mad2sSgo1, a major splice variant of Sgo1, functions in centriole cohesion where it is regulated by Plk1Bub1 regulates chromosome segregation in a kinetochore-independent mannerHuman Wapl is a cohesin-binding protein that promotes sister-chromatid resolution in mitotic prophaseProtein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2Structure and function of the PP2A-shugoshin interactionSeparase is recruited to mitotic chromosomes to dissolve sister chromatid cohesion in a DNA-dependent mannerShugoshin enables tension-generating attachment of kinetochores by loading Aurora to centromeresBub1 mediates cell death in response to chromosome missegregation and acts to suppress spontaneous tumorigenesisThe Renaissance or the cuckoo clockThree wise centromere functions: see no error, hear no break, speak no delayCohesin is dispensable for centromere cohesion in human cellsPolyoma small T antigen triggers cell death via mitotic catastropheSgo1 recruits PP2A to chromosomes to ensure sister chromatid bi-orientation during mitosis.Mitotic centromeric targeting of HP1 and its binding to Sgo1 are dispensable for sister-chromatid cohesion in human cellsStructure of the human cohesin inhibitor WaplThe Aurora kinase Ipl1 maintains the centromeric localization of PP2A to protect cohesin during meiosis.Sgo1 regulates both condensin and Ipl1/Aurora B to promote chromosome biorientation.Protein Phosphatases Involved in Regulating Mitosis: Facts and HypothesesFrequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinomaBod1 regulates protein phosphatase 2A at mitotic kinetochoresHistone chaperone NAP1 mediates sister chromatid resolution by counteracting protein phosphatase 2ASGO1 maintains bovine meiotic and mitotic centromeric cohesions of sister chromatids and directly affects embryo developmentA Centromere-Signaling Network Underlies the Coordination among Mitotic EventsXenopus Shugoshin 2 regulates the spindle assembly pathway mediated by the chromosomal passenger complexAnalysis of all protein phosphatase genes in Aspergillus nidulans identifies a new mitotic regulator, fcp1Ska3 is required for spindle checkpoint silencing and the maintenance of chromosome cohesion in mitosisThe closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progressionLoss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.Suppression of Ser/Thr phosphatase 4 (PP4C/PPP4C) mimics a novel post-mitotic action of fostriecin, producing mitotic slippage followed by tetraploid cell deathCRL4-DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation.Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylationDefective sister chromatid cohesion is synthetically lethal with impaired APC/C function.Solving the shugoshin puzzleZNF198 stabilizes the LSD1-CoREST-HDAC1 complex on chromatin through its MYM-type zinc fingers
P2860
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P2860
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
description
2006 nî lūn-bûn
@nan
2006 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@ast
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@en
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@en-gb
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@nl
type
label
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@ast
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@en
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@en-gb
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@nl
prefLabel
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@ast
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@en
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@en-gb
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@nl
P2093
P921
P3181
P1433
P1476
PP2A is required for centromeric localization of Sgo1 and proper chromosome segregation
@en
P2093
Hongjun Shu
Hongtao Yu
Marc C Mumby
Nadir A Mahmood
Zhanyun Tang
P304
P3181
P356
10.1016/J.DEVCEL.2006.03.010
P407
P50
P577
2006-03-30T00:00:00Z