The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
about
MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascadesCentral role of the gut epithelial barrier in the pathogenesis of chronic intestinal inflammation: lessons learned from animal models and human geneticsA bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKKgamma to dampen the host NF-kappaB-mediated inflammatory responseMycobacteria in Crohn’s disease: how innate immune deficiency may result in chronic inflammationThe molecular chaperone HSP70 binds to and stabilizes NOD2, an important protein involved in Crohn diseaseInsights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin.Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognitionITCH K63-ubiquitinates the NOD2 binding protein, RIP2, to influence inflammatory signaling pathwaysInvolvement of linear polyubiquitylation of NEMO in NF-kappaB activationSite-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activationA role for Erbin in the regulation of Nod2-dependent NF-kappaB signalingRole for erbin in bacterial activation of Nod2A novel motif in the Crohn's disease susceptibility protein, NOD2, allows TRAF4 to down-regulate innate immune responsesPathogen recognition and inflammatory signaling in innate immune defensesFunction of Nod-like receptors in microbial recognition and host defenseA critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activationSelective death of autoreactive T cells in human diabetes by TNF or TNF receptor 2 agonismChronic inflammation: importance of NOD2 and NALP3 in interleukin-1beta generationUbiquitin signaling in immune responsesRoles of NOD1 (NLRC1) and NOD2 (NLRC2) in innate immunity and inflammatory diseasesNOD-Like Receptors: Master Regulators of Inflammation and CancerRIP2 activity in inflammatory disease and implications for novel therapeuticsGenetically determined epithelial dysfunction and its consequences for microflora-host interactionsNod2: A Critical Regulator of Ileal Microbiota and Crohn's DiseaseCYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune SignalingSignals from within: the DNA-damage-induced NF-kappaB responseCentral roles of NLRs and inflammasomes in viral infectionThe ubiquitin-editing enzyme A20 restricts nucleotide-binding oligomerization domain containing 2-triggered signalsPellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitisA NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptideInflammatory bowel diseaseUbiquitin signalling in the NF-kappaB pathwayIkappaB kinase beta phosphorylates the K63 deubiquitinase A20 to cause feedback inhibition of the NF-kappaB pathway.Distinct TLR- and NLR-mediated transcriptional responses to an intracellular pathogen.Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice.Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation.The IKK complex, a central regulator of NF-kappaB activationHSCARG downregulates NF-κB signaling by interacting with USP7 and inhibiting NEMO ubiquitination.Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways.Cigarette smoke extract (CSE) delays NOD2 expression and affects NOD2/RIPK2 interactions in intestinal epithelial cells.
P2860
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P2860
The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO
description
2004 nî lūn-bûn
@nan
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@ast
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@en
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@en-gb
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@nl
type
label
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@ast
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@en
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@en-gb
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@nl
prefLabel
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@ast
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@en
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@en-gb
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@nl
P921
P3181
P1433
P1476
The Crohn's disease protein, N ...... lation of a novel site on NEMO
@en
P2093
Andrew Wilkins
John M Asara
P304
P3181
P356
10.1016/J.CUB.2004.12.032
P407
P577
2004-12-29T00:00:00Z