Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
about
Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligaseThe transforming activity of Ski and SnoN is dependent on their ability to repress the activity of Smad proteinsDual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexesSmad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressorTranscriptional activating activity of Smad4: roles of SMAD hetero-oligomerization and enhancement by an associating transactivatorIdentification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoNUnraveling insulin-like growth factor binding protein-3 actions in human diseaseGlucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3Smads bind directly to the Jun family of AP-1 transcription factorsTransforming growth factor beta1 induces nuclear export of inhibitory Smad7BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formationAntagonistic effects of Smad2 versus Smad7 are sensitive to their expression level during tooth developmentNovel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activationSmad3-Smad4 and AP-1 complexes synergize in transcriptional activation of the c-Jun promoter by transforming growth factor betaThe role of FAST-1 and Smads in transcriptional regulation by activin during early Xenopus embryogenesisDirect binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene.Transcriptional control by the TGF-beta/Smad signaling systemXSmad2 directly activates the activin-inducible, dorsal mesoderm gene XFKH1 in Xenopus embryos.Alternative trans-splicing of Caenorhabditis elegans sma-9/schnurri generates a short transcript that provides tissue-specific function in BMP signaling.Tiul1 and TGIF are Involved in Downregulation of TGFbeta1-induced IgA Isotype Expression.Can't get no SMADisfaction: Smad proteins as positive and negative regulators of TGF-beta family signals.Genomic characterization of Wilms' tumor suppressor 1 targets in nephron progenitor cells during kidney development.A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity.Two hits revisited againCharacterization of a bone morphogenetic protein-responsive Smad-binding element.Partial loss of Smad signaling during in vitro progression of HPV16-immortalized human keratinocytesThe DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway.Determinants of specificity in TGF-beta signal transduction.The tumor suppressor Smad4/DPC4 and transcriptional adaptor CBP/p300 are coactivators for smad3 in TGF-beta-induced transcriptional activation.Transforming growth factor beta/Smad3 signaling regulates IRF-7 function and transcriptional activation of the beta interferon promoter.Smad4 overexpression causes germ cell ablation and leydig cell hyperplasia in transgenic mice.Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells.Recent advances in understanding transforming growth factor beta regulation of orofacial development.18α-glycyrrhetinic acid down-regulates expression of type I and III collagen via TGF-Β1/Smad signaling pathway in human and rat hepatic stellate cellsRegulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members.Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein.A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling.Molecular regulatory mechanism of tooth root development.Partial Müllerian Duct Retention in Smad4 Conditional Mutant Male Mice
P2860
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P2860
Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4
description
1997 nî lūn-bûn
@nan
1997 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@ast
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@en
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@en-gb
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@nl
type
label
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@ast
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@en
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@en-gb
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@nl
prefLabel
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@ast
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@en
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@en-gb
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@nl
P2093
P2860
P921
P3181
P356
P1476
Heteromeric and homomeric inte ...... tivity of Smad3 and Smad4/DPC4
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.17.5.2521
P407
P577
1997-05-01T00:00:00Z