HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.
about
CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment.Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosisTimely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cellsBuilding a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora ADDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movementThe Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosomeA TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridgingTPX2 regulates the localization and activity of Eg5 in the mammalian mitotic spindleCep55, a microtubule-bundling protein, associates with centralspindlin to control the midbody integrity and cell abscission during cytokinesis"HURP on" we're off to the kinetochore!The Ran Pathway in Drosophila melanogaster MitosisTime-lapse imaging of neuroblastoma cells to determine cell fate upon gene knockdownAurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubulesInhibition of apoptosis by oncogenic hepatitis B virus X protein: Implications for the treatment of hepatocellular carcinomaPlk1- and beta-TrCP-dependent degradation of Bora controls mitotic progressionFundamental limits to position determination by concentration gradientsCDK-1 Inhibition in G2 Stabilizes Kinetochore-Microtubules in the following MitosisThe Ndc80 complex: integrating the kinetochore's many movements.Localized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cellsA centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytesChromosome congression in the absence of kinetochore fibres.Microtubule-dependent regulation of mitotic protein degradation.Kinesin-12 Kif15 targets kinetochore fibers through an intrinsic two-step mechanismEnzyme localization can drastically affect signal amplification in signal transduction pathways.Abnormal kinetochore-generated pulling forces from expressing a N-terminally modified Hec1.HURP expression-assisted risk scores identify prognosis distinguishable subgroups in early stage liver cancer.Cyclin G-associated kinase promotes microtubule outgrowth from chromosomes during spindle assembly.Phospho-regulation of DDA3 function in mitosisFunctional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase.Expanding applications of chemical genetics in signal transduction.Hepatoma upregulated protein expression is involved in the pathogenesis of human breast carcinogenesis.HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells.CKAP2 is a spindle-associated protein degraded by APC/C-Cdh1 during mitotic exit.Tripolin A, a novel small-molecule inhibitor of aurora A kinase, reveals new regulation of HURP's distribution on microtubules.Involvement of DNA-dependent protein kinase in normal cell cycle progression through mitosis.High KIF18A expression correlates with unfavorable prognosis in primary hepatocellular carcinomaPrognostic value of discs large homolog 7 transcript levels in prostate cancer.Hurp deficiency in mice leads to female infertility caused by an implantation defect.cis-Expression QTL analysis of established colorectal cancer risk variants in colon tumors and adjacent normal tissue.
P2860
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P2860
HURP controls spindle dynamics to promote proper interkinetochore tension and efficient kinetochore capture.
description
2006 nî lūn-bûn
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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
HURP controls spindle dynamics ...... efficient kinetochore capture
@nl
HURP controls spindle dynamics ...... efficient kinetochore capture.
@ast
HURP controls spindle dynamics ...... efficient kinetochore capture.
@en
type
label
HURP controls spindle dynamics ...... efficient kinetochore capture
@nl
HURP controls spindle dynamics ...... efficient kinetochore capture.
@ast
HURP controls spindle dynamics ...... efficient kinetochore capture.
@en
prefLabel
HURP controls spindle dynamics ...... efficient kinetochore capture
@nl
HURP controls spindle dynamics ...... efficient kinetochore capture.
@ast
HURP controls spindle dynamics ...... efficient kinetochore capture.
@en
P2860
P3181
P356
P1476
HURP controls spindle dynamics ...... efficient kinetochore capture
@en
P2093
Guowei Fang
P2860
P304
P3181
P356
10.1083/JCB.200511132
P407
P50
P577
2006-06-12T00:00:00Z